High-Risk Cytogenetics
High-Risk Cytogenetics Quiz
Test your knowledge of high-risk cytogenetics and its impact on patient treatment outcomes. This quiz covers key concepts related to cytogenetic abnormalities, treatment responses, and statistical analyses in high-risk patients.
- 11 thought-provoking questions
- Multiple choice format for easy answering
- Assess your understanding of recent research findings
Which of the following cytogenetic abnormalities were not considered in the analysis?
T(4;14)
T(14;20)
T(14;16)
Del17p
What proportion of patients in the DVd group had high cytogenetic risk abnormalities?
57%
44%
29%
16%
14%
MPFS for DVd vs Vd at first relapse in patients with high-risk abnormalities was...?
12.6 vs 6.2 months
16.6 vs 6.6 months
20.1 vs 8.4 months
29.8 vs 7.5 months
Did the addition of daratumumab to bortezomib and dexamethasone impact the rate of AEs in any specific cytogenetic risk subgroup?
Yes, the rate of AEs was higher in the favorable risk subgroup
Yes, the rate of AEs was higher in the intermediate risk subgroup
No significant difference in AE rates among the subgroups
AE rates were not reported in the paper
What percentage of patients in the high-risk subgroup achieved a very good partial response (VGPR) or better with DVd treatment?
Less than 10%
Approximately 20%
Approximately 40%
Approximately 60%
Was the comparison of VGPR in the high-risk subgroup statistically significant?
Yes
No
P-value not reported
What was the relative risk reduction in disease progression or death for patients with high-risk cytogenetics with DVd at first relapse?
20%
40%
60%
80%
What was the time to response for patients with high-risk cytogenetics vs standard risk patients?
Same time to response
Faster time to response
Delayed time to response
The discontinuation rate due to TEAEs for patient with standard risk receiving DVd was 8%. What was the rate for high-risk patients receiving DVd?
7%
8%
9%
10%
11%
Fill in the blank: DVd more than ________ rates of complete response or better vs Vd alone in patients with high-risk cytogenetics
Halved
Double
Tripled
This was not reported
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