Pharmaceutics

Which of the following is not a dosage form?

Gel

Suspension

Tablet

All of the above are dosage forms

Which of the following is not an example of an excipient?

FD&C yellow #6

Lactose

Penicillin powder

Corn starch

Absorption is from site of administration to systemic circulation.

True

False

Inhibition of P-gp will result in _______ in absorption.

Increase

Decrease

Only ______ drugs are sufficiently lipid soluble to cross the cell membranes

Ionized

Basic

Polar

Non-ionized

Weak acids are more readily absorbed in the....

Small intestine

Stomach

Large intestine

Liver

The protonated form of weak acids is...

Non-ionized

Ionized

The protonated form of weak bases is...

Non-ionized

Ionized

Most drugs are absorbed by...

Active transport

Facilitated diffusion

Passive diffusion

The most common cytochrome P450 enzymes used in metabolism...

CYP3A3

CYP3A4

CYP3A2

CYP3A5

The cytochrome P450 enzymes are considered part of the first pass effect.

True

False

When taking CYP3A4 substrate medications, one should avoid which beverage?

Orange Juice

Milk

Grapefruit Juice

Soda

Which plasma protein typically binds basic drugs?

Albumin

Alpha 1 acid glycoprotein (AAG)

Biopharmaceutics definition?

To develop optimized drug therapy that reaches the site of action at the right time, right dose, and for the correct duration, and not to reach other sites in the body where the drug toxicities occur

The area of pharmacy embracing the relationship between the physical, biologic, and metabolic sciences as they apply to drugs, dosage forms, and drug action

The area of study embracing the relationship between the physical, chemical, and biologic sciences as they apply to drugs, dosage forms, and drug action

Pharmaceutical equivalents or pharmaceutical alternatives whose rate and extent of absorption do not show a significant difference

Pharmaceutics definition?

To develop optimized drug therapy that reaches the site of action at the right time, right dose, and for the correct duration, and not to reach other sites in the body where the drug toxicities occur

The area of study embracing the relationship between the physical, chemical, and biologic sciences as they apply to drugs, dosage forms, and drug action

Drug products that contain identical amounts of the identical active drug ingredient

To develop optimized drug therapy that reaches the site of action at the right time, right dose, and not to reach other sites in the body where the drug toxicities occur

Pharmaceutical equivalents definition?

Pharmaceutical equivalents or pharmaceutical alternatives whose rate and extent of absorption do not show a significant difference

Drug products that contain identical amounts of the identical active drug ingredient

Drug products that contain the identical therapeutic moiety or its precursor but not necessarily in the same amount or dosage form or as the same salt or ester

Drug products that contain almost identical amounts of the identical active drug ingredient

Pharmaceutical alternatives definition?

Drug products that contain almost identical amounts of the identical active drug ingredient

Drug products that contain the identical therapeutic moiety or its precursor but not necessarily in the same amount or dosage form or as the same salt or ester

Drug products that contain the identical active ingredients or its precursor but not necessarily in the same amount or dosage form or as the same salt or ester

Pharmaceutical equivalents or pharmaceutical alternatives whose rate and extent of absorption do not show a significant difference

Bioequivalent drug products definition?

Pharmaceutical equivalents or pharmaceutical alternatives whose rate and extent of absorption do not show a significant difference

Pharmaceutical equivalents or pharmaceutical alternatives whose rate of absorption do not show a significant difference

Pharmaceutical equivalents or pharmaceutical alternatives whose rate and extent of absorption show a significant difference

Drug products that contain the identical therapeutic moiety or its precursor but not necessarily in the same amount or dosage form or as the same salt or ester

Pharmaceutics

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