Quiz 1 seminar (just kidding)
Understanding BTK Inhibitors: Quiz
Test your knowledge on Bruton’s Tyrosine Kinase (BTK) inhibitors and their mechanisms. This quiz covers key concepts related to TKIs, resistance mechanisms, and advanced sequencing methods in cancer research.
- 5 Multiple Choice Questions
- Focused on BTKIs and genetic research
- Evaluate your understanding and learn more!
What the is the main aim of the presented article ?
To unveil the impact of of certain mutations of the binding affinities only
To know the resistance mechanism against non-covalent BTKIs
To understand the mechanism of actions of BTKIs
None of the above
The names of most TKIs end with ?
-tinib
-vomab
-azol
All of the above
What is the most important finding of the study ?
The non-C481 mutations impair the binding of a number of inhibitors to BTK. In so doing, several of these mutations paradoxically hinder BTK catalytic activity yet allow effective B-cell–receptor signaling and AKT pathway activation despite exposure to covalent and noncovalent BTK inhibitors.
The the non-C481 mutations impair the binding Of non-covalent brutons TKIs only
The non-C481 mutations hinder both the AKT and BTK pathways upon Exposure to non-covalent and covalent BTKIs
None of the above
Choose the correct regarding single cell DNA sequencing ?
Used to interrogate genetically individual cells
Used to understand the genetic heterogeneity of sub-clonal cells in the tumor
The DNA in each cell is sequenced individually
In this research, the researchers did not use this technique
The name of the study from which the patients were taken is:
BRUIM
BRUIN
YUPPY
BRAIN
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