Medical Oncology Quiz for Resident Rotators 2020

 

This is a short pre- and post-rotation quiz designed to assess your knowledge on medical oncology before and after rotating with us. This will also prepare you for the PSBIM. Reference is the latest edition of Harrison's Principles of Internal Medicine.
This is a formative evaluation and will not affect your final grade for the rotation. This will also help us assess how we teach our rotators.
Thank you!

Medical Oncology Knowledge Assessment

Welcome to the Medical Oncology Quiz for Resident Rotators. This quiz has been designed to evaluate your understanding of medical oncology, covering various critical topics. It serves as both a pre- and post-rotation learning tool and is intended to enhance your knowledge before the PSBIM.

Key Features:

• Multiple choice questions covering essential topics in oncology
• Formative evaluation to assist in your learning
• Anonymous and non-graded assessment

26 Questions6 MinutesCreated by LearningOncologist42

What is the ECOG performance status of a patient capable of only limited self-care and is confined to bed or chair >50% of waking hours?

ECOG 2

ECOG 3

ECOG 4

ECOG 5

A 65-year-old male diagnosed with non-small cell lung cancer presented with dyspnea. On work-up, a right-sided pleural effusion was noted. What is the best treatment plan?

Refer to Pulmo for pleurodesis with doxycycline, talc or bleomycin.

Refer to TCVS for immediate chest tube insertion.

Do thoracentesis.

Start the patient on diuretics.

A 55-year-old female presented with a 6-month history of painless hematuria. On work-up, she was noted to have squamous bladder cancer. What is the most likely etiologic agent?

Epstein-Barr virus

Benzene

Vinyl chloride

Schistosomiasis

A 40-year-old female, 5 pack-year smoker, with a 3-month history of dyspnea and occasional hemoptysis, was found to have a peripherally located pulmonary mass. What is the most likely immunohistochemical findings of this mass?

(+) TTF1 or napsin A

(+) p40 or p63

(+) Synaptophysin

(+) Calretinin

A 50-year-old male office worker with a heavy smoking history presented with a 5-mm solitary pulmonary nodule on chest x-ray. What is the next step?

Request for a CT scan with thin sections through the nodule.

Refer to IR for CT-guided biopsy of the pulmonary nodule.

Refer to TCVS for immediate resection of the pulmonary nodule.

Retrieve old chest x-ray films for comparison.

A 45-year-old male presented with a 10-mm pulmonary nodule with spiculated borders on imaging. He was a past heavy smoker who stopped 5 years ago. Which of the following characteristics portends the highest risk for a malignancy in this patient?

Size of the pulmonary nodule

His age

Spiculated borders on imaging

His smoking history

What is the most common histologic subtype of lung cancer?

Adenocarcinoma

Squamous cell carcinoma

Small cell carcinoma

Large cell carcinoma

What is the most appropriate treatment for a 75-year-old male diagnosed with stage IV EGFR-mutated lung adenocarcinoma?

Crizotinib

Cisplatin or carboplatin + gemcitabine

Docetaxel

Erlotinib

A 65-year-old male presented with cough, hemoptysis, weight loss, occasional dyspnea and a right supraclavicular node. Biopsy of the node showed squamous cell carcinoma. Chest CT scan showed a right lower lobe mass and pleural effusion, which was positive for carcinoma on pleural fluid cytology. What is the best management for this patient?

Refer to TCVS for resection of the right lower lobe mass.

Refer to Med Onco for systemic chemotherapy.

Refer to Rad Onco for radiotherapy.

Refer to Rad Onco and Med Onco for concurrent chemoradiation.

A 25-year-old female presents with a palpable soft movable tender mass measuring 2x2 cm at the right breast. She is currently on her first day of menstruation. On what day of the menstrual cycle should the patient be re-examined?

Day 2-3

Day 4-5

Day 5-7

Day 8-10

What molecular subtype of breast cancer has the worst prognosis?

Luminal A

Luminal B

Her2-enriched

Basal

A 40-year-old female with stage III breast cancer undergoing chemotherapy complained of paresthesias of the extremities. Which of the following chemotherapeutic agents is the most likely cause of her complaint?

Doxorubicin

Cyclophosphamide

Paclitaxel

Carboplatin

A 40-year-old female presented with a 5 cm x 5 cm fixed hard nontender left breast mass with multiple ipsilateral axillary nodes. Core needle biopsy showed invasive ductal carcinoma, ER/PR-, Her2neu 3+. What is the best management for this patient?

Breast conservation surgery with sentinel lymph node dissection + chemotherapy + trastuzumab + endocrine therapy ± radiotherapy

Breast conservation surgery with axillary lymph node dissection + chemotherapy + trastuzumab ± radiotherapy

Mastectomy with sentinel lymph node dissection + chemotherapy + endocrine therapy + trastuzumab ± radiotherapy

Mastectomy with axillary lymph node dissection + chemotherapy + trastuzumab ± radiotherapy

A 35-year-old female patient with locally advanced left breast cancer underwent mastectomy with adjuvant chemotherapy (doxorubicin, cyclophosphamide, and docetaxel), trastuzumab, and radiotherapy. She was brought to the emergency room due to sharp chest pain exacerbated with coughing and inspiration and relieved by sitting up and leaning forward. Which of the following is the most probable etiology of her symptom?

Doxorubicin

Trastuzumab

Radiotherapy

Disease progression

What is the recommended frequency of mammography among breast cancer patients undergoing routine surveillance after treatment?

Every 3 months for 1 year, then annually thereafter

Every 6 months for 1 year, then annually thereafter

Every 6 months for 2 years, then annually thereafter

Annually

A 40-year-old male presented with palpitations and easy fatigability. He was noted to be anemic and colonoscopy showed a colonic mass. At which part of the colon is the mass most likely located?

Ascending colon

Transverse colon

Descending colon

Sigmoid colon

What is the most frequent and initial site of metastasis in colorectal cancer?

Lung

Liver

Bone

Brain

What is the minimum number of lymph nodes that should be sampled to accurately define tumor stage in colorectal cancer?

10

12

14

16

According to the USPSTF, what is the recommended guideline for colorectal cancer screening in a 60-year-old asymptomatic, male patient?

Colonoscopy every 5 years

FOBT every year

CT colonography every 5 years

FIT every 6 months

A 40-year-old male presenting with bowel movement changes was diagnosed to have sigmoid adenocarcinoma on colonoscopy. He underwent resection with the tumor penetrating beyond the muscularis layer and 5 out of 16 lymph nodes were positive for carcinoma. What is the best management for this patient?

Radiotherapy

Chemotherapy

Concurrent chemoradiotherapy

Surveillance

Which of the following describes cardiovascular dysfunction secondary to trastuzumab?

Dose-related

Usually reversible

Pathognomonic pathologic finding is myofibrillar dropout

Mechanism is due to free radical damage

Chemotherapy with bleomycin is best known for what possible late effect?

Cardiomyopathy

Decreased renal function

Pulmonary fibrosis

Bone marrow aplasia

What is the most common cause of malignant spinal cord compression?

Lung cancer

Prostate cancer

Breast cancer

Colorectal cancer

A 64-year-old male patient with non-small cell lung cancer presents with neck and facial swelling, dyspnea and cough. What is the most appropriate treatment for this patient?

Glucocorticoids

Diuretics

Radiation therapy

Chemotherapy

A 55-year-old female patient with metastatic breast cancer presents with headache, vomiting and seizures. Imaging showed multiple enhancing lesions of various sizes with surrounding areas of low-density edema. What is the best initial treatment for this patient?

Dexamethasone

Whole brain radiation

Shunt placement

Oxygen therapy