General biot huiii
Four (4) Biological Molecules: Carbohydrates; Lipids; Proteins (Enzymes); Nucleic Acids
❖ Describe carbohydrates, lipids, proteins and nucleic acids as biological molecules based on its structure and function
❖ Identify the different types and examples of carbohydrates, lipids, proteins and nucleic acids
❖ Identify different factors that affect enzyme activity
❖ Describe different examples of enzymes
Four (4) Biological Molecules: Carbohydrates; Lipids; Proteins (Enzymes); Nucleic Acids
❖ Describe carbohydrates, lipids, proteins and nucleic acids as biological molecules based on its structure and function
❖ Identify the different types and examples of carbohydrates, lipids, proteins and nucleic acids
❖ Identify different factors that affect enzyme activity
❖ Describe different examples of enzymes
Are large, organic molecule such as carbohydrates, lipids, proteins, and nucleic acids. Most of them are organic compounds and the functional group determines their chemical properties. Biomolecules have a huge variety of functions, such as storing energy, protection, etc.
Biological Molecules
Carbohydrates
Primary energy source of energy on all living organisms Made up of hydrogen, carbon and oxygen molecules
Biological Molecules
Carbohydrates
Monosaccharides
Disaccharides
Polysaccharides
Sakcharon”- sugars made up of sugars classified either as simple or complex
Biological Molecules
Carbohydrates
Monosaccharides
Disaccharides
Polysaccharides
Simple sugars with only one sugar unit Building blocks in the formation of complex sugars Highly soluble in water The most common simple sugar is composed mainly of 6 carbon atoms
Biological Molecules
Carbohydrates
Monosaccharides
Disaccharides
Polysaccharides
Examples
Ribose and deoxyribose
Milk products
Glucose
Also called as dextrose (blood sugar)
Galactose
The sweetest known sugar in fruits such as ripe mangoes, melon, sugar apple (atis), corn, honey etc.
Mannose
Form the backbone of RNA and DNA
Fructose
Small amounts in fruits; plants, microbes and animals
Simple sugars with two sugars When two monosaccharides combine this cause this leads to the loss of water molecule known as condensation or dehydration synthesis Absorption of nutrients and buildup of molecules
Biological Molecules
Carbohydrates
Monosaccharides
Disaccharides
Polysaccharides
Examples
Maltose (malt sugar)
Can disaccharides be broken down into simple sugar?
Sucrose (table sugar)= glucose + fructose -
Combination of two glucose molecules Found in cereals and sprouting grains
Hydrolysis,
is found in sugarcane, sugar beets, carrots, and other sweet fruits.
Glucose + galactose = Lactose(milk sugar)
Milk sugar or animals
Polysaccharide found in the outer coverings of crustaceans, fungi and insects. Hydrate and protect soft tissues. Use for medical, industrial, pharmaceutical and biotechnological purposes.
Starch
Glycogen
Cellulose
Chitin
Found in plant cell wall serves as fiber source that reduce cholesterol in the body.
Starch
Glycogen
Cellulose
Chitin
Storage carbohydrate in animals accumulated in the liver and muscle cells.
Starch
Glycogen
Cellulose
Chitin
Storage carbohydrates in plants composed entirely hundred of glucose molecules found in potato tubers, cassava, carrots, corn, and cereals
Starch
Glycogen
Cellulose
Chitin
Derived from the Greek word “lipos” meaning fat hydrophobic molecules (non-polar)
Lipids
Fats
Saturated fatty acids
Unsaturated fatty acids
Lipids composed of one or more glycerol (alcohol containing carbon) and fatty acid molecules
Lipids
Fats
Saturated fatty acids
Unsaturated fatty acids
Solvent for fat-soluble vitamins and hormones Building blocks of cell membranes Prevents water loss and heat loss Source and storage of energy. It provides twice as much energy per pound as carbohydrates.
True
False
Solid at room temperature (found in animals; lard, margarine and butter)
Lipids
Fats
Saturated fatty acids
Unsaturated fatty acids
Liquid state at room temperature (found mainly on plants; vegetable oil, corn oil, canola, olive oil)
Lipids
Fats
Saturated fatty acids
Unsaturated fatty acids
Blood fats circulate in the bloodstream along with cholesterol
Waxes
Steroids
Cholesterol
Triglycerides
Sphingolipids
Composed of four-fused rings of carbon Examples are cholesterol, bile salts, sex hormones, and vitamin D.
Waxes
Steroids
Cholesterol
Triglycerides
Sphingolipids
Simple lipids composed of a long chain of alcohol bonded to a fatty acid. Found in plants, bees, ears Primary components of cosmetics, food products and medical supplies
Waxes
Steroids
Cholesterol
Triglycerides
Sphingolipids
Liver produces bile found in meat products, poultry, eggs and dairy products.
Waxes
Steroids
Cholesterol
Triglycerides
Sphingolipids
Found in the brain, lungs, and nerve tissues. Serves as surfactants reducing tension on the lungs to maintain its shape.
Waxes
Steroids
Cholesterol
Triglycerides
Sphingolipids
Made up of one or more peptides
Proteins
Amino Acids
Peptide
Proteins
Bonds between amino acids Polypeptide - chain of amino acids
Proteins
Amino Acids
Peptide
Proteins
Can be the hardest to digest. Are large, complex molecules made up of 20 varying amino acids.
Proteins
Amino Acids
Peptide
Proteins
Building blocks of protein polymers in chain composed of carbon, hydrogen, oxygen, nitrogen, and sometimes sulfur
Proteins
Amino Acids
Peptide
Proteins
Definition
Regulatory or Signal proteins
Special type of proteins that speeds up chemical reactions such as metabolism
Storage Proteins
Referred to as hormones that regulates body fun ctions. Includes growth factors that influence growth and development of an organism
Defense proteins
Allow movement and cause muscle contraction Regulate body temperature
Structural proteins
Aid in transport of molecules such as oxygen, water, sugar and ions in and out of the cell
Transport proteins
Forms the structural parts of the cells and tissues
Enzymatic proteins
Serves as reserves of amino acids, which can be used later on to nourish the growth and development of organisms.
Contractile proteins
Bodies-defense system against disease causing organisms
Examples
Defense proteins
Keratin - in hair and fingernails Collagen - most abundant fibrous protein found on vertebrates connective tissues that supports the skin, tendons and ligaments.
Structural proteins
Insulin - regulates glucose concentration in the blood
Enzymatic proteins
Storage Proteins
Contractile proteins
Actin and myosin
Food digestion involves different enzymes: Amylase - for starch Protease - for protein Lipase - for lipid
Antibodies - fights antigen
Transport proteins
Channel and carrier protein in the cell membrane Hemoglobin in RBC help in oxygen transport
Regulatory or Signal proteins
Ovalbumin - found in egg white
Special proteins that speed up the chemical reaction including photosynthesis, respiration and protein synthesis A biological catalysts that lower the activation energy of reaction hence speeding up the reaction some enzymes help break down large molecules into smaller ones, others build up large molecules from smaller ones and some enzymes help change one molecule into another.
ENZYMES
Activators
Inhibitors
PH
Temperature
Substrate Concentration
Is the amount of substrate present that can be turned into a product. The lower the substrate concentration, the lower will be the rate of reaction. The higher the substrate concentration, the higher the frequency of reaction.
ENZYMES
Activators
Inhibitors
PH
Temperature
Substrate Concentration
(factors) Most enzymes are active only at body temperature (37 degrees Celsius), but become inactive at very low temperature. Different enzymes have optimum working temperatures.
ENZYMES
Activators
Inhibitors
PH
Temperature
Substrate Concentration
(factors) enhance enzyme activity
ENZYMES
Activators
Inhibitors
PH
Temperature
Substrate Concentration
(factors) block substrate from binding with the said enzyme
ENZYMES
Activators
Inhibitors
PH
Temperature
Substrate Concentration
(factors) Changes in pH can disrupt weak interaction that hold proteins together and can cause an enzymes to denature (lose their precise shape). Once an enzymes has denatured, it will not function again.
ENZYMES
Activators
Inhibitors
PH
Temperature
Substrate Concentration
The physical carrier of of inheritance that is passed from parents to offspring.
Nucleic Acids
NUCLEOTIDE
Functions of Nucleic Acids - Storage of genetic information Protein synthesis for transmit and express of genetic information
True
False
Made up of a five-carbon sugar, phosphate group, nitrogenous base.
Nucleic Acids
NUCLEOTIDE
Guanine (G) Adenine (A)
Deoxyribonucleic acid (DNA)
Ribonucleic acid (RNA)
PURINES
PYRIMIDINES
Cytosine (C) Uracil (U) Thymine (T)
Deoxyribonucleic acid (DNA)
Ribonucleic acid (RNA)
PURINES
PYRIMIDINES
The structure of DNA as a double-stranded helix molecule was first described by James Watson and Francis Crick in 1953.
True
False
An organic molecule used for short-term energy storage and transport in the cell. Known as the energy currency of the cell. It is composed of three parts:
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Is the transfer of energy from one chemical reaction to another.
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
The three phosphate groups in an ATP molecule are negatively charged. Having the same charge will tend to repel from each other. Thus, this means that the three phosphate groups are in an unstable arrangement. The third phosphate group is so eager to get further away from the two phosphate groups.
True
False
An organic molecule used for short-term energy storage and transport in the cell. Known as the energy currency of the cell. It is composed of three parts:
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
The formation of ATP to ADP is reversible. ATP and ADP are like charged and uncharged forms of a rechargeable battery. ATP (charged battery) has energy that can be used to power cellular processes or reactions. Once the energy is used up, ADP (uncharged battery/dead battery) needs to be recharged in order to be used as a power source. ATP regeneration reaction is the reverse of hydrolysis reaction
True
False
Energy is released
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
Energy is absorbed
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
Is the transfer of energy from one chemical reaction to another.
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
A process in which a phosphate group is added to a molecule
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
Removes water in a molecule
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
The remaining free phosphate group and low-energy molecule is called
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
A bond between them is broken through ______(water-mediated breakdown) reaction releasing energy.
ATP (/ Adenosine Triphosphate)
Energy coupling
Exergonic reaction
Endergonic reaction
Phosphorylation
Dehydration synthesis
Adenosine diphosphate (ADP).
Hydrolysis
Photosynthesis & Cellular respiration
❖ Explain the importance of chlorophyll and other pigments
❖ Identify the major features and chemical events in photosynthesis. (light and dark reaction)
❖ Differentiate photosynthesis and cellular respiration
Photosynthesis & Cellular respiration
❖ Explain the importance of chlorophyll and other pigments
❖ Identify the major features and chemical events in photosynthesis. (light and dark reaction)
❖ Differentiate photosynthesis and cellular respiration
Process by which plants converts solar or light energy into chemical energy for food production.
Photosynthesis
Mesophyll.
Stomata
Chloroplasts
Photosynthesis takes place in the leaves of the plants, specifically in the middle layer known as
Photosynthesis
Mesophyll.
Stomata
Chloroplasts
Where gases enter and exits the leaves.
Photosynthesis
Mesophyll.
Stomata
Chloroplasts
Part of plant cell responsible for the process of photosynthesis
Photosynthesis
Mesophyll.
Stomata
Chloroplasts
Important parts of the chloroplast:
Thylakoids
Green pigment embedded in the thylakoid that absorbs light.
Chlorophyll
Thick fluid inside the membrane
Stroma
Stacks of thylakoids
Chlorophyll a) Photosystems
Tiny disc-shaped interconnected membranous sacs
Grana
light-absorbing molecule in the thylakoid membrane
Convert light energy from the sun into chemical energy. Occurs in the thylakoid where photosystems exist. Starts with photosystem II going to photosystem I Produces oxygen, ATP and NADPH (nicotinamide adenine dinucleotide phosphate),
Light Reactions / Light-Dependent Reactions
Chemiosmosis
Dark Reactions / Light-Independent Reactions / Calvin Cycle (Calvin-Benson Cycle)
Diffusion or movement of hydrogen ions through ATP synthase
Light Reactions / Light-Dependent Reactions
Chemiosmosis
Dark Reactions / Light-Independent Reactions / Calvin Cycle (Calvin-Benson Cycle)
Convert carbon dioxide from the atmosphere into carbohydrates or sugars. Does not require the presence of light In the Calvin Cycle, chemical energy (from the light reactions) and CO2 (from the atmosphere) are used to produce organic compounds (like glucose). Occurs in the stroma Produces glucose, ADP and NADP+ ( is the oxidized form of NADPH)
Light Reactions / Light-Dependent Reactions
Chemiosmosis
Dark Reactions / Light-Independent Reactions / Calvin Cycle (Calvin-Benson Cycle)
Carbon Reduction
Converting CO2 to carbohydrates begins Adding of electrons and energy to the carbon dioxide molecule. Uses NADPH and some ATP from light reactions 3PG is reduced to G3P (a carbohydrate)
Electron Transport Chain
ATP is combined with the rest of G3P molecules to form RuBP molecules RuBP can combine with CO2 to continue the carbon reactions again.
Regeneration of RuBP
Captures the CO2 from the atmosphere
Redox Reactions (Oxidation - reduction)
Electrons are passed from one member of the transport chain to another in a series of redox reactions.
Carbon Fixation
Involve the transfer of electrons to another. One loses electrons is oxidized, while the other gains electrons is reduced.
Aerobic Vs. Anaerobic Pathway of Cellular respiration
❖ Explain major features of glycolysis, Krebs cycle and electron transport chain
❖ Identify the different parts of mitochondria and their function for cellular respiration
❖ Differentiate aerobic and anaerobic respiration
❖ Determine the advantages of fermentation.
❖ Explain concepts explaining the process of fermentation.
Aerobic Vs. Anaerobic Pathway of Cellular respiration
❖ Explain major features of glycolysis, Krebs cycle and electron transport chain
❖ Identify the different parts of mitochondria and their function for cellular respiration
❖ Differentiate aerobic and anaerobic respiration
❖ Determine the advantages of fermentation.
❖ Explain concepts explaining the process of fermentation.
Small, specialized cellular organelles that produce energy in the form of ATP. “Powerhouse of the cell”
MITOCHONDRIA
Cellular Respiration
Aerobic Respiration
Anaerobic Respiration
Is the process that occurs in the mitochondria of organisms (animals and plants) to break down sugar in the presence of oxygen to release energy in the form of ATP. This process releases carbon dioxide and water as waste products.
MITOCHONDRIA
Cellular Respiration
Aerobic Respiration
Anaerobic Respiration
Cellular respiration - reverse chemical reaction of photosynthesis. This chemical equation of cellular respiration is also a redox reaction. Because glucose has lost an electron, it is said to be oxidized. Meanwhile, oxygen has gained some electrons, so it is said to be reduced.
True
False
Used to generate usable ATP energy in order to support many other reactions in the body. ATP is particularly important for energetically unfavorable reactions that would otherwise not occur without an energy input. True or false is it important?
True
False
Is a set of metabolic reactions that take place in the presence of oxygen, occurring in a cell to convert chemical energy into ATPs.
MITOCHONDRIA
Cellular Respiration
Aerobic Respiration
Anaerobic Respiration
Is the process of creating energy without the presence of oxygen.
MITOCHONDRIA
Cellular Respiration
Aerobic Respiration
Anaerobic Respiration
Aerobic Pathway of Cellular Respiration 3 Stages
Electron Transport Chain
Occurs in cristae Electrons are passed from one member of the transport chain to another to produce ATP. The common feature of all electron transport chains is the presence of a proton pump to create a proton gradient across a membrane.
Krebs Cycle / Citric Acid Cycle
Second stage that occurs in the mitochondrial matrix and generates a pool of chemical energy (ATP, NADH, and FADH2) from the oxidation of pyruvate, the end product of glycolysis.
Glycolysis
First stage of aerobic pathway in metabolism of glucose from “glyco” meaning sugar and “lysis” meaning to split occurs in cytosol of the mitochondria. Harvesting of energy by breaking down glucose into pyruvate. Takes place in both aerobic and anaerobic organisms..
The process of sugars being broken down by enzymes in the absence of oxygen
Fermentation
Lactic Acid Fermentation
Alcoholic Fermentation
NADH transfers its electrons directly to pyruvate, generating lactate or lactic acid ( C3H6O3) as a byproduct. Occurs in muscle cells, bacteria that make yogurt, and red blood cells
Fermentation
Lactic Acid Fermentation
Alcoholic Fermentation
In which NADH donates its electrons to a derivative of pyruvate, producing ethanol. Alcohol fermentation by yeast produces the ethanol found in alcoholic drinks like beer and wine.
Fermentation
Lactic Acid Fermentation
Alcoholic Fermentation
Using suitable microorganisms and specified conditions different kinds of fermentation products are formed namely:- Wine, Beer , Biofuels, Yoghurt, Pickles, Bread Sour foods containing lactic acid Certain antibiotics and vitamins
True
False
Using suitable microorganisms and specified conditions different kinds of fermentation products are formed namely:- Wine, Beer , Biofuels, Yoghurt, Pickles, Bread Sour foods containing lactic acid Certain antibiotics and vitamins
True
False
Other than the food industry, there are many other areas where the fermentation process is used. Methane is produced by fermentation in sewage treatment plants and freshwater sediments.
True
False
Fermentation can make food nutritious, digestible and flavoured. There are many benefits of consuming fermented food. It improves digestion and helps to maintain intestinal bacteria It has an anti-cancer effect. Improves immune system Reduces lactose intolerance
True
False
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