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Epilepsy and mechanism

Having two seizures at least 24 hours apart due to specific identifiable cause is considered as epilepsy.
True
False
In which channels, glycine promote membrane Hyperpolarisation & reduce the Neuronal responsivene?
Sodium Channel
Calcium Channel
Sodium Pottasium Pump
Chloride Channel
Glycine is an important Powerful ____________ in the CNS
Pre Synaptic Inhibitory NT
Pre Synaptic Excitatory NT
Post Synaptic Inhibitory NT
Post Synaptic Excitatory NT
Where are Glycine Receptor that mediate fast inhibitory neurotransmission present in our body ?
Frontal Lobe
Brain Stem
Spinal Cord
Option 2 and 3
All the 3 options
Glycine acts DIRECTLY at NMDA receptors in all the regions of the CNS
True
False
What is the purpose of an EEG (electroencephalogram) in diagnosing epilepsy?
To measure brain activity and detect abnormal electrical patterns
To assess heart function
To evaluate lung capacity
To monitor blood pressure
What is the term for a seizure that affects only one hemisphere of the brain?
Generalized seizure
Focal seizure
Absence seizure
Myoclonic seizure
Which of the following is NOT a potential cause of epilepsy?
Genetic factors
Head injury
Metabolic Change
Infection
What is core component of EpiGly DGM?
Lycine
Glycine
Methyl
Dimethyl Ether
Which age group is most commonly affected by juvenile myoclonic epilepsy?
Adolescents
Adults
Infants
Older adults
What are the Key factors of EpiGly DMG?
Acts as Biological Rheostat
Increases Hyperpolarization in PNS
Addresses Pain Perception
Both 1 and 3 options
All the 3 options
What is the mode of action for EpiGly?
GABAminergic
Refractive Seizure Mechanism
Glycinergic
Glutametergic
Which medical device is used to monitor Seizure ?
ECG
Ultra Sound Scan
EEG
X-Ray
Jake, a college student who is highly sensitive to flashing lights. While attending a music concert with intense light shows, he suddenly experiences what seems like a seizure. His body responds with uncontrolled movements and muscle contractions due to the overwhelming visual stimuli. Is this condition Epilepsy or Not?
Yes
No
Which part of the brain is commonly associated with temporal lobe epilepsy?
Frontal lobe
Parietal lobe
Temporal lobe
Occipital lobe
What is the term for a seizure that involves sudden loss of muscle tone?
Focal seizure
Absence seizure
Tonic-clonic seizure
Atonic seizure
What are the other issues involved in epilepsy management
Oxidative Stress
Cognition
Neurochemical Changes
Quality of Life
All the above
Match the Epileptic Drugs with their Mode of Action.
Zonisamide
Modulates synaptic Neurotransmitter release
Carbamazepine
Blocks the voltage gated Sodium Channels in the NMDA R
Levitracetam
Increases the concentration of GABA
Lamotrigine
Blocks the Ca Channels which may prevent the spread of seizure discharge to other cells
Sodium Valproate
Suppresses the release of excitatory Neurotranmitter
What is the term used for failure of 2 or 3 AEDs to control seizure or lack of seizure control with in a defined time period ?
Frontal Lobe Epilepsy
Juvenile Myoclonic Epilepsy
Tardive Dyskinesia
Refractory Epilepsy
Match the Etiology with Clinical Condition
Genetic
Auto-immune encephalopathy
Immune
Pyridoxin dependent Seizures
Idiopathic
Stroke/ Tumor
Metabolic
Juvenile Myoclonic Epilepsy
Structural
Frontal Lobe Epilepsy
Which of the following activites that CANNOT be done by patient with epilepsy?
Driving
Swimming
Working in an industrail setup
All the Above
Which seizure characterized by brief, jerking spasms of a muscle or muscle group?
Myoclonic Seizures
Grandmal Seizure
Absence Seizures
Tardive Dyskinesia
What is the term for a seizure that involves sudden loss of consciousness without convulsions?
Focal seizure
Absence seizure
Myoclonic seizure
Atonic seizure
What is the full form DGM
Di-Methoxy Glycine
Dipeptide Methyl Glycine
Dimethyl Glycine
Dihydroxy Methoxy Glycine
What is the PTS of EpiglyDMG?
384.41
381.41
384.81
348.41
According to our Visual Aid, 30% of Epileptics are ___________
Simple Partial Epilepsy
Complex Epilepsy
Refractory Epileptics
Juvenile Myoclonic Epilepsy
What is the Concentration of DMG in Epigly DMG ?
125mg/5ml
250mg/ml
100mg/5m
150mg/5ml
What is the Energy Buffer for faster recovery in ailing Epileptics?
Phosphorus
Peptocreatine
Phosphorus Creatine
Phosphocreatine
Glycine augments anti-epileptic therapy by reducing ________ and pain perception
Myospasm
Infantile Spasms
Mephthalspasm
Neuro-Muscular Spasms
Which of the following is NOT a seizure co-morbidities
Cognitive Decline
Muscle Spasms
Intractable Seizures
Echolilia
Glycine improves cognition through regulation of Neuronal Excitability in the ______________________ Formation
Cortex
Medulla Oblongata
Cerebellam
Hippocampus
Glycine is a Biological _______________
Resistor
Rheostat
Conductor
Modulator
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