GIT infection 1

A 32 year old male has traveled to Brazil for 3 months. During that period he went to a traditional sea food restaurant after a while he noticed cramps and has developed severe diarrhea. When he went to the hospital he was diagnosed with cholera. What is the average period required to develop his symptoms.
A) few hours -5 days
B) 3-5 days
C) 1-3 days
D)1 week
Which of the following is at highest risk to be infected by V.cholerae:
A) pregnant women
B) male
C)AB blood type
D) low gastric acidity
What is the action of cholera toxin on the intestinal cells:
A) increase the flow out of electrolytes by activation of ion channels.
B) decrease the absorption of water
C) damage the wall of the intestines
D) none
Which of the following is not true regarding cholera:
A) intestinal infection
B) invasive diarrheal disease
C) caused by V.cholera endotoxin
D) major epidemic disease
One of the serotype of V.cholerae that has a toxic effect is:
A. O114
B. O139
C. O45
D. O11
A 58-year-old woman has progressively worsening epigastric pain. Upper endoscopy showed a 4-mm duodenal ulcer; biopsy specimens revealed mild gastritis with no evidence of malignancy. Histologic evaluation of the tissue showed infection with Gram negative bacilli..A. Which one of the following is the most likely causative organism:
A. klebsiella
B. E.coli
C. Helicobacter pylori
D. Streptococcus Pneumoniae .
For the previous scenario, what is the most appropriate treatment:
A. PPI b.d. + clarithromycin 500mg b.d + Amoxicillin 500 mg b.d. Minimum of 14 days
B. PPI b.d. + clarithromycin 500 mg b.d +Tetracycline 120mg b.d. Minimum of 7 days
C. PPI b.d. + metronidazole 250mg b.d +subcitrate 120mg b.d. Minimum of 28 days
PPI + Bismus + clarihtromycin for 14 days
A 26-year-old African American woman presented with a 1-month history of intermittent, burning epigastric abdominal pain that was moderately severe in intensity. She also noted nausea and vomited once. The patient denied having signs and symptoms of melena, hematochezia, or hematemesis. How you can diagnose her disease
Serology by ELIZA
Antigen in stool
Blood culture
Stool culture
The previous patient diagnosed as Hpyori infection and not known to have any allegy towards any medication but she recently received clarithromycin for UTI. How would you treat her
Triple therapy: PPI, amoxicillin, clarithromycin
Triple therapy: PPI, amoxicillin, metronidazole
Quadrable therapy: BISMUTH , PPI ,amoxicillin , levofloxacin
Quadrable therapy: PPI,amoxicilin , bismuth, clarithromycin
Best medium for H.Pylori is
Blood agar
TCBS
Skirrow's
Macongey
Most sensetive and reliable non-invasive method for h.pylori infection is
Serology IgM
Antigen in stool
Stool culture
Urea breath test
3-H.Pylori culture in:
A.Aerobic
B.Anaerobic
C.microaerophilic
4-Lymphoma associated with H. Pylori infection is:
A.Lymphoblastoma
B. MALT Lymphoma
C. Burkitt’s lymphoma
D. Follicular lymphoma
How to differentiate between salmonella and shigella?
A. Gram stain
B. Motility
C. Lactose fermentation
A 17- year- oldd maan had aa grilled chicken dinner with his friends. Three days later he went to the hospital with secere abdominal cramps; stools were bloody and pus cells were present. Culture under microaerophilic conditions revealed Gram-negative, oxidase positive rods. The most probable causative agent is:
A) Vibrio cholerae
B) Salmonella (typhoid fever)
C) Campylobacter jeuni
D) Shigella flexneri
E) Helicobacter pylori
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