PP cycle 3 2019

A detailed infographic that highlights key concepts related to familial hypercholesterolemia and common metabolic disorders, featuring illustrations of lipid profiles, affected organ systems, and relevant medical imagery.

Familial Hypercholesterolemia and Related Disorders Quiz

Test your knowledge about metabolic disorders, particularly familial hypercholesterolemia and other related conditions affecting health. This quiz consists of 20 insightful questions designed to assess your understanding of various diseases and their implications.

Explore questions related to diabetic foot, emphysema, and atherogenesis.
Evaluate your grasp of genetic disorders like phenylketonuria and albinism.
Challenge yourself with questions that cover diagnosis criteria and complications in chronic diseases.

20 Questions5 MinutesCreated by AnalyzingWhale341

Choose false sentences about familial hypercholesterolemia: Select one or more:

Patients often present with tendon xanthomas

It is inherited in autosomal recessive pattern

Patients do not have higher risk of developing IHD

Mutations causing the disease usually affect LDL-R or ApoB

Choose correct pairing of disease name and the cause of this disease: Select one or more:

Phenylketonuria: defect in homogentisic acid dioxygenase

Homocystinuria: defects of methionine metabolism

There is no correct answer

Albinism: melanin deficiency

Diabetic foot: Select one or more:

Is a lesion of all layers of skin in the foot, including necrosis or gangrene

Results from hyperglycemia that produces oxidative stress on nerve cells

Develops as a result of peripheral neuropathy within foot

Develops as a result of arterial disease and other forms of diabetic macroangiopathy

Toxic effects of high glucose level on endothelial cells typically include:

2. Polyol pathway activation

Nonenzymatic glycosylation

Decrease in NO production

Blood-circulating protein enzymatic decarboxylation of amino acids

Four students had their lipid profiles tested. Which student(s) show abnormal results? Select one or more:

TG = 110 mg/dL, Ch total = 160 mg/dL, HDL = 70 mg/dL, LDL = 95 mg/dL

TG = 311 mg/dL, Ch total = 220 mg/dL, HDL = 40 mg/dL, LDL = 160 mg/dL -

TG = 130 mg/dL, Ch total = 185 mg/dL, HDL = 67 mg/dL, LDL = 82 mg/dL

TG = 220 mg/dL, Ch total = 190 mg/dL, HDL = 35 mg/dL, LDL = 140 mg/dL

In phenylketonuria (PKU): Select one or more:

Mouse-like odor of urine is present

Hyperphenylalaninemia occurs

Symptoms do not include mental retardation

Ochronosis is a prominent symptom

A 23-year-old woman known to have an inborn error of metabolism is planning her first pregnancy. She is advised by her physician to begin a phenylalanine-free diet before conception and to continue this diet throughout pregnancy. Mutation in which gene does the woman most likely have?

PKU

CFTR

LDL

PAH

Choose false sentences: Select one or more:

The eyes are never affected in albinism

Symptoms of albinism include whitish hair and light sensitivity

Mutations in the same gene result in tyrosinemia type I and II

Defects in tyrosinase activity cause albinism

Diabetes mellitus has to be diagnosed by medical doctor when is detected: Select one or more:

Casual glycemia ≥ 180mg%

OGTT result ≥ 200mg%

OGTT result ≥ 140mg%

Fasting glycemia ≥ 100mg%

Indicate correctly specific complications resulting from diabetic microangiopathy. Select one or more:

Ophthalmopathy

Nephropathy

Visceropathy

Oncopathy

Which of four patients would you diagnose with metabolic syndrome? Select one or more:

BMI=22, hypertension, normoglycemia, TG=250 mg/dL, HDL=88 mg/dL

BMI=28, normal blood pressure, hyperglycemia, TG=300 mg/dL, HDL=36 mg/dL

BMI=35, central obesity, hypertension, hyperglycemia, TG=200 mg/dL, HDL=35 mg/dL .-

BMI=32, central obesity, hypertension, normoglycemia, TG=280 mg/dL, HDL=36 mg/dL .-

You will diagnose diabetic ketoacidosis in patient presenting:

Polyuria and polydipsia

Kussmaul respiration

Headaches and vomiting

Deficiency of the homogentisic acid oxidase enzyme

Emphysema is:

A slowly developing fibrotic degeneration of pulmonary interstitium.-

A disease which often is triggered by acute pneumonia

Based on easy to explain pathomechanism

Often mistakenly diagnosed as asthma -

Beyond any controversy, COPD chronic obstructive pulmonary disease definitely does not include:

Chronic bronchitis

Late stages of bronchial asthma

Emphysema

Early stages of acute bronchial asthma

Atelectasis:

Of the compression type can lead to decrease of perfusion

In hyaline membrane syndrome is of a focal nature

In hyaline membrane syndrome is a result of decreased perfusion

Of the resorption type involves whole lungs

COPD - Select one or more:

Is a disease caused by single, well defined etiological factor

Is one of the important causes of disability among people over 60 years of

Is a disease caused by infection with Gram negative bacteria

Is the second most important cause of death from the respiratory tract diseases

Choose correct sentences about celiac disease: Select one or more:

It can only affect adult patients

Histopathology examination usually reveals blunting of villi, crypt hyperplasia and lymphocyte infiltration

It is an autoimmune disorder of the small intestine, caused by chronic intolerance of gluten protein

Complications of celiac disease include nutritional deficiencies caused by chronic malabsorption

PP cycle 3 2019

Familial Hypercholesterolemia and Related Disorders Quiz

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