Final 16.8.2022

The skin lesion which is not associated with disorders of pigmentation is;

The skin lesion which is not associated with disorders of pigmentation is;

The skin lesion which is not associated with disorders of pigmentation is;

The skin lesion which is not associated with disorders of pigmentation is;

A 60-year-old woman with small cell carcinoma of the lung notes rounding of her face, upper truncal obesity, and muscle weakness. Physical examination reveals thin, wrinkled skin, abdominal striae, and multiple purpuric skin lesions. The patient’s blood pressure is 175/95 mm Hg. Laboratory studies will likely show elevated serum levels of which of the following hormones?

A 40 year old male presented with right testicular enlargement. Orchidectomy was performed and histological diagnosis of Seminoma was given. An identical tumour aries in the ovary is called as

A 10 year old boy complains of intermittent abdominal pain. Endoscopy fails to demonstrate peptic ulcer or chronic gastritis. The clinician suspects that the patient may have a heterotopic rest of gastric mucosa that is producing enough acid to cause ulceration of adjacent mucosa. Which of the following is the most likely diagnosis?

A 70 yr old man who is hypertensive presents to ER with complaint of severe occipital headache that he describes as worst headache I ever had, on examination he has nuchal rigidity, and CT scan brain is advised. What do you think the patient is suffering from?

An 8-year-old African American boy presents to the emergency department complaining of severe pain in both legs. The pain began after the boy attended a pool party and spent much of the day swimming. He reports that he has suffered from severe bouts of back and chest pain in the past owing to a preexisting medical condition. Routine laboratory studies demonstrate a severe anemia. You place the child on oxygen, begin aggressive intravenous fluid hydration, and call the blood bank to prepare for a blood transfusion. What is most likely the diagnosis?

A 15-year-old girl presents to the emergency department with a petechial rash, bleeding of the oral mucosa, fatigue, and a history of recurrent sinus infections over the past 2 months. She does remember having had a bad flu- like virus about 3 months ago that caused her to miss 4 days of school. There is no hepatosplenomegaly on examination. Laboratory tests reveal anemia, neutropenia, and thrombocytopenia. There are no abnormal cell types seen on peripheral blood smear. You decide to admit the patient to the hospital and you schedule a bone marrow biopsy. What does the bone marrow biopsy show? (multiple)

A 28-year-old man presents to his GP with a 4cm mobile anterior neck mass. A fine needle aspirate is performed which reveals cells with ‘orphan Annie eye’ nuclei and psammoma bodies. What is the most likely diagnosis?

An 8-year-old boy presents to the emergency department with a swollen right knee. He denies a history of trauma to the knee. Physical examination reveals a warm, swollen, erythematous joint with a significant effusion. Upon taking a family history, you learn that two of the boy's maternal uncles suffer from a bleeding disorder. Laboratory tests reveal a prolonged PTT, a normal PT, and a normal bleeding time. To provide the proper treatment, you immediately order a clotting factor assay. What if the diagnosis?

A 30-year-old man presents to the emergency room with a cold, pale left foot with absent pedal pulse. He complains of loss of feeling in his left foot after several months of painful bouts in the involved area. He has smoked two packs of cigarettes a day for the past 10 years. You order an arterial biopsy of the affected region, which demonstrates intimal proliferation and thrombi with inflammatory infiltrates. You explain to the patient that the condition is associated with his smoking and that the most effective treatment is smoking cessation.

Alzheimer disease is the most common cause of dementia in the elderly. Autopsy of the patient died of this disease shows characteristic histological features in the brain which of the following is not a feature of this disease.

A 20-year old female complained of multiple bullae and vesicles on the face, axilla, and trunk. The lesions were noted to rupture easily that leaves shallow erosions. This disorder is caused by autoantibodies that result in dissolution of intercellular attachments within the epidermis and mucosal epithelium. The autoantibodies are directed against

In a 30 year old female breast lump of 2cm is excised having irregular borders. Histopathology report shows sclerosing adenosis. Which lesion is not a part of benign proliferative breast disease?

A 26-year-old pregnant woman presents to your office for a checkup. She states that her pregnancy has been proceeding smoothly, although she has been feeling more tired than she expected. Her physical examination is largely unremarkable except for marked pallor. You order serum studies and find that she has decreased hematocrit, decreased ferritin, and increased total iron-binding capacity. Her peripheral blood smear shows red blood cells that are both microcytic and hypochromic. You reassure her that these findings are most likely associated with her pregnancy status and recommend iron supplements.

A 57 year old woman with anemia is found to have a decreased Vitamin B12 level. Antibodies to intrinsic factor are identified. Levels of all other vitamins are within normal limits. Which of the following is most likely to be associated with this condition?

A 30-year-old man with Marfan syndrome presents to the emergency room with severe, sudden, tearing chest pain radiating to the abdomen and back. The pain has progressively O X shifted downward over the last several hours. On physical examination, he is found to have asymmetric pulses and a pericardial friction rub. ECG studies are normal and angiography shows an ascending aortic abnormality. You schedule the patient for immediate surgical repair. Which of the following statements is false?

A 62 year gentleman presents to the clinic with a 5 cm painless neck mass as well as diarrhoea for the past 3 months . A biopsy is taken and he is subsequently diagnosed with medullary carcinoma. Which of the following features is consistent with medullary carcinoma

A 34-year-old female was brought to the physician. The patient has sinusitis, cough, skin nodules, significant purpura also noted on the extremities as well as carpal tunnel syndrome. The patient's CBC shows eosinophilia. Pulmonary function tests show an obstructive pattern improved with beta-agonist and diagnosis of asthma was made. Which of the following is correct about her condition?

A 50 yr old lady presents with weakness and dizziness, on examination diffuse hyperpigmentation can be seen on buccal mucosa & skin creases.lab reports show eosinophilia, lymphocytosis & neutropenia. What is your diagnosis?

Nephritic syndrome is characterised by all except:

A 30-year-old woman arrives at the emergency room complaining of fatigue and dark-colored urine. While obtaining the history of her present illness, you learn that she has been recovering from a recent bout of pneumonia, for which she had been treated appropriately by her primary care physician with a course of antibiotics. Physical examination reveals an enlarged spleen and slight scleral icterus. You obtain a blood sample and decide to order a direct Coomb test. What is do you suspect?

An old lady 58 years of age c/o gradual on set of bone pain, anorexia, constipation, polyuria, polydipsia and muscular weakness. Her serum Ca and Alk phosphatase were raised and PO4 was low. She was probably suffering from

A 70-year-old white woman presents to the clinic complaining of severe unilateral headaches and transient blurry vision. Upon physical examination, you find that there is Ex pain upon palpation of her temples. When laboratory tests reveal an elevated ESR, you initiate treatment with prednisone to prevent possible blindness. You also ask for an ophthalmological consult and you order a temporal artery biopsy, which you suspect will reveal granulomatous inflammation and the presence of giant cells. The most likely diagnosis of this patient is:

A 45-year-old obese white man presents to the clinic for an annual checkup. He has no complaints other than occasional headaches. During the history, you find that he is a smoker and has a family history of heart disease. His physical examination is significant for mild obesity and a blood pressure of 160/100. You suggest lifestyle changes including weight loss, a low-salt diet, and smoking cessation, and you also prescribe hydrochlorothiazide to treat his condition. Which of the following statement false?

A 60 year old man presents to his physician because of progressive dysphagia, first to solids and then to liquids. Endoscopy reveals a large fungating mass 2cm above the Gastroesophageal junction. Biopsy of the mass shows that the glands have extended into muscular layer and contain large hyperchromatic nuclei. A diagnosis of esophageal adenocarcinoma is made. Which of the following conditions can result in the development of this lesion?

The following Changes occur in minimal change glomerulonephritis:

A 10-year-old girl presents to the clinic with fever, malaise, migratory polyarthritis, and a blanching erythematous ring-shaped rash over her proximal extremities. On further questioning, you find out that she suffered from a severe sore throat 2 to 3 weeks ago. Serum studies demonstrate an ESR of 100 and a positive anti–streptolysin O titer. You worry that she may suffer from valvu-lar heart disease during her adult years as a result of her current condition. What if the diagnosis?

A 25 year old lady suffers from secondary amennorhea (loss of mensus) and galactorhea, she is diagnosed the most common pituitary tumor, the lady is suffering from

A 6-year-old boy presents to your office complaining of fatigue, fever, and a history of recurrent epistaxis (nose bleeds) and urinary tract infections. He has an enlarged liver and spleen and a petechial rash over his entire body. Concerned, you send him for some blood y tests, which demonstrate pancytopenia with the presence of multiple blast forms. You fear that a bone marrow biopsy may demonstrate cells that would stain positive for TDT and CALLA. Which of the following statements if false?