Quiz 1 Semester 3

A newborn with severe diarrhea is found to have an inherited defect in a glucose transporter resulting in glucose/galactose malabsorption, necessitating a glucose and galactose-free diet. Which of the following is the transport protein responsible for entry of glucose into the intestinal enterocyte?
GLUT-2
GLUT-5
SGLUT-1
SGLUT-2
GLUT-3
A 43-year-old woman presents with dysphagia to solids and liquids, bland regurgitation. During this time, she has lost about 20 pounds. The patient is scheduled for esophageal imaging and motility testing. The esophagogram during a barium swallow shows a dilated esophagus with an area of distal stenosis and esophageal manometry tracings during a wet swallow shows a high lower esophageal sphincter (LES) opening pressure and uncoordinated peristalsis. These findings are consistent with which of the following diagnoses?
 
Achalasia
Diffuse esophageal spasm
Esophageal carcinoma
GERD
Schatzki ring
A 70-year-old woman presents with abdominal pain, microcytic anemia, and weight loss. Colonoscopy with biopsy confirms colon cancer. Which of the following best describes colonic function?
Absorption of Na+ in the colon is under hormonal control by anti-diuretic hormone
Bile acids enhance absorption of water from the colon
Secretion of HCO3- occurs in exchange for absorption of Cl-
Net water absorption accounts for 7500 ml
In proximal colon, Na+ absorption occurs via indapamide-sensitive channels
A 34-year-old man with long-standing gastro-oesophageal reflux disease is reviewed in clinic. He has recently switched from ranitidine to omeprazole. What is the main benefit of omeprazole compared to ranitidine?
More effective histamine receptor antagonism
Irreversible blockade of H+/K+ ATPase
Decreased post-prandial acid production
Longer half-life
Increased gastric motility
Intolerance to table sugar ingestion could be caused from the deficiency of:
Lactase
Sucrase
Amylase
Hydrolase
Maltase
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