An antigen reacts with a/an
Receptor of a sensitized T cell
Antibody
Zymogen
Both first and second choices are correct
When an antigen reacts with an antibody, it is guaranteed to exhibit an immune response.
True
False
Refers to the macromolecules that are capable of triggering an immune response by inducing the information of antibodies or sensitized T cells in an immunocompetent host
Immunoblast
Immunogen
Either
Neither
All immunogens are antigens, but not all antigens are immunogens.
True
False
What do immunogens induce in order to fight off the foreign body and elicit an immune response?
The formation of combat cells
The growth of bacteria
The formation of antibodies
The releasing of enzymes
All of the following are factors involving immune response; EXCEPT:
Biological properties
Nature of immunogen
Genetic coding of MHC
Immunogen processing and presentation
AOTA
Which of the following age groups are at higher risk of disease due to their biological properties?
Adolescents
Geriatric
Toddlers
Adult
Biological property that is affected by factors such as fatigue, stress, and malnutrition
Age
Route of inoculation
Overall health
Genetic capacity
The higher the _____________ the higher the immune response
Age
Overall health status
Genetic capacity
Dose
_____________ is the ability of an immunogen to stimulate a host's response
Protectivity
Health
Immunity
Immunogenicity
Predisposition linked to MHC
Genetic capacity
Dose
Age
Route of inoculation
These are non-immunogenic materials that when combined with a carrier, create new antigenic determinants
Adjuvants
Foreignness
Haptens
Epitopes
Epitopes are also called
Favored site
Determinant site
Both
Neither
Epitopes are the ___________ of the immunogen.
Binding portion
Blinding portion
Key portion
Foreign part
Which of the following is NOT a characteristic of immunogenecity?
Foreignness
Chemical composition
The ability to be processed and presented with MHC molecules
Molecular gravity
Immunogens must have a molecular weight of at least ______________ to be recognized by the immune system.
5,000 daltons
10,000 microns
10,000 daltons
100,000 daltons
Most active immunogens typically have a molecular weight of over
1 million daltons
100,000 daltons
10,000 daltons
500,000 daltons
The greater the molecular weight the more _______ the molecule is as an immunogen
Weak
Ineffective
Inefficient
Potent
The increase in molecular weight is directly proportional to the increase of immune response
True
False
If a substance is more foreign, thus it is more likely to be immunogenic.
True
False
What trait of immunogen is described in this statement: if a substance is more foreign, thus it is more likely to be immunogenic.
Foreignness
Molecular weight
Chemical composition or molecular complexity
Ability to be processed and presented with MHC molecules
______________ are powerful immunogens because they are made up of a variety of units known as amino acids
Carbohydrates
Proteins
Lipids
NOTA
_____________ are less immunogenic than protein because they are smaller than proteins and have a limited number of sugers available to create their structures.
Carbohydrates
Proteins
Lipids
NOTA
Pure _____________ and ____________________ are not immunogenic by themselves except when they are attracted to a suitable carrier molecule.
Carbs and sugars
Lipids and proteins
Lipids and nucleic acids
Nucleic acids and starch
Epitopes are recognized by _________ or ___________
Antigens or antibodies
B cells or t cells
B cells or plasma cells
None of the above
[type of epitope] amino acids following one another on a single chain
Singular
Conformational
Multiple
Linear
[type of epitope] results from the folding of one chain or multiple chains.
Singular
Conformational
Multiple
Linear
Which of the following are characteristics of Haptens? (2)
Adaptability
Immunogenicity
Antigenicity
Aluminum salts that are a component of Hepatitis B vaccines are known as what?
Epitopes
Haptens
Autoantigens
Adjuvants
It is a substance administered with an immunogen that increases the immune response in order to provide immunity to a particular disease.
Haptens
Autoantigens
Adjuvants
Epitopes
What do haptens target to accelerate adaptive immune response?
T cells
Antigen presenting cells
Immunogenic cells
NOTA
Haptens should meet the criteria of causing minimal toxicity to humans, which is why more susbtances are not approved at this time.
True
False
Antigens that belong to the host; if an immune response occurs, it may result to an autoimmune disease.
Autoantigens
Alloantigens
Heteroantigens
Heterophile antigens
Antigens from other members of the host's species, and are capable of eliciting an immune response.
Autoantigens
Alloantigens
Heteroantigens
Heterophile antigens
Alloantigens are important to consider when doing procedures such as blood typing one patient.
True
False
Antigens from other species such as animals, plants, or microorganisms
Autoantigens
Alloantigens
Heteroantigens
Heterophile antigens
Heteroantigens that exist in unrelated plants and animals but are either identical or closely related in structure so that antibody to one will cross react with an antigen of the other.
Autoantigens
Alloantigens
Heteroantigens
Heterophile antigens
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