PM cycle 2 single choice questions only

What is the most common germ cell tumor in children younger than 3 years of age?

A 10 cm tumor of the right ovary is composed of immature mesenchymal cells, immature cartilage and neuroepithelium. The most likely diagnose is:

A 23-year-old woman has a spontaneous abortion at 15 week’s gestation. The male fetus is small for gestational age and malformed, with syndactyly of the third and fourth digits of each hand. The placenta also is small and shows 0.5-cm grape like villi scattered among morphologically normal villi. Chromosomal analysis of placental tissue is most likely to which of the following karyotypes:

Apocrine metaplasia of the breast:

In natural history of LSIL the most possible scenario is that:

How many pregnancies implant ectopically?

The presence of osteoblastic metastases in an older male is strongly suggestive of advanced:

PSA is produced by:

Clinical and experimental observations suggest that all of the following factors are involved in the pathogenesis of prostate carcinoma EXCEPT:

Krukenberg tumor is a metastatic carcinoma of the:

The most common histologic type of cervical carcinoma is:

The presence of structures resembling primitive glomeruli, the so-called Schiller-Duvall bodies, is characteristic of

A 62-year-old childless woman noticed a bloody vaginal discharge twice during past month. Her last menstrual period was 10 years ago. ... Pelvic examination showed that uterus is ... In situ with no palpable adhered masses. There are no cervical ... Or masses. Her Body Mass Index is 35. Her medical history indicates that for the past 30 years she had hypertension & type 2 Diabetes Mellitus. An endometrial biopsy specimen is most likely to have which of the following:

Which of the following sentences regarding phyllodes tumor are true

Which of the following lesions corresponds to endometrial intraepithelial neoplasia of high grade?

A clinical study of women diagnosed with ovarian neoplasms reveal that that 1 in 200 develop masculinizing signs and symptoms, including hirsutism, acne, breast atrophy, and amenorrhea. Which of the following neoplasms is most likely to produce these symptoms?

How many breast cancers are related to specific inherited mutations?

Where can we find apocrine metaplasia?

Some type of breast lesion that creates “single file”

Which of the following tumors occurs most often in the ovary?

Which of the following carcinomas is locally invasive but rarely forms metastases in LN and distal sides?

In which cell function is BRCA1, a gene mutated in women with familial breast carcinoma, involved

A benign breast tumor composed of loose fibroblastic stroma containing ductlike epithelium-lined spaces of various forms and sizes is called

The microscopic finding of CIN II of the uterine cervix in a biopsy from a 30-year-old female

Typical changes in cells due to HPV infection:

A woman 50 years old, 10 cm nodule in right breast that is well circumscribed. Histologically leaf like structure and high amount of stromal … epithelial component is also present:

Infiltrative lobular carcinoma of breast is characterized histologically by:

Tumor in woman made from cartilage, mesenchymal end epithelial tissue

Which of the following breast carcinomas have smooth outline on mammography:

5-year survival in patient with breast carcinoma less than 0,9 cm in diameter is approximately:

True for leiomyoma:

Endometrial adenocarcinoma grade 1:

Most common testicular neoplasm:

The presence of CIN1 on biopsy is most likely associated with:

Which of the following pathologic changes most strongly suggests an increased risk of carcinoma of the breast in a 45-year-old female?

Inflammatory carcinoma of the breast is histologically characterized by:

The most common ovarian cancer is?

The peak age incidence of CIN is about:

Prognosis of breast carcinoma is influenced by all the following EXCEPT:

High- grade squamous intraepithelial lesion corresponds to:

Which of the listed abnormalities describes the characteristics cytopathic effect by infection with HPV?

A 28-year-old woman at her third trimester of her third pregnancy discovered a lump in her right breast. Physician palpated a 2-cm discrete, freely movable mass beneath nipple. After birth of a term infant, the mass appears to decrease slightly. The infant breastfeeds without difficulty. Which of the following is the most likely diagnosis?

A 66-year-old childless woman noticed a blood-tinged vaginal discharge twice during past month. Her last menstrual period was 14 years ago. Bimanual pelvic examination shows that uterus is normal size, with no palpable adnexal masses. There are no cervical erosions or masses. Her medical history indicates that for past 30 years she has had hypertension and = Marker used to assess secretory cells (metastatic prostatic carcinoma) = Marker used to assess secretory cells (metastatic prostatic carcinoma) type 1 Diabetes Mellitus, which is treated with insulin injections. An endometrial biopsy is most likely to show which of the following:

Female 50 y.o. Gradual enlargement of the left nipple over several years. Breast skin is unchanged. No abnormal discharge and LN are normal. In mammography well circumscribed tumor with diameter of 12 cm. Histology shows connective tissue with mitosis. You suspect:

Mutations in BRCA1 increase risk of carcinoma in breast and carcinoma of:

Squamous carcinoma of the penis gives metastases to the following LN:

Most common neoplasm of testis is:

Male with gynecomastia examination reveals tumor in testis and lack of increased AFP and HCG

Osteoblastic metastases to bone results from:

Child with tumor in left testis of 2.5 cm, increased AFP and α1-antitrypsin:

Main etiologic factors in prostatic hyperplasia:

70 y.o. Male has metastases to vertebra. Which is primary carcinoma:

Primary cervical carcinoma:

Congenital abnormalities of the penis:

Histology of ovarian tumor shows cells with pale cytoplasm, large nucleus, and irregular nucleolus divided by connective tissue with lymphocytic infiltrate. Diagnosis:

45 year old patient. Ultrasound shows 9 cm tumor in the abdominal cavity. Histology shows undifferentiated adenocarcinoma and chondrosarcoma. Diagnosis

Malignant tumors of the endometrium:

Hydatidiform mole – risk of choriocarcinoma:

Most common reason of death due to carcinoma of cervix:

Chorionic villi are not present in:

60-year-old woman with bleeding. What kind of examination is first you do?

Which of the following endometrial abnormalities can be seen in association with granulosa cell tumors?

What is serum PSA level used as the upper limit of normal:

Which of the following lesions is characterized by thinning of the epidermis, hydropic degeneration of the basal cells, hyperkeratosis and dermal fibrosis with mononuclear

Cervical carcinomas typically include all of the following carcinomas except:

Nests of endometrial stroma, glands or both, found in the myometrium between the muscle bundles are referred as:

Majority of hereditary ovarian cancers seem to be caused by mutations in:

Overexpression of HER-2 gene is almost always caused by:

Most of the breast cancers are located in the:

CIN II indicates:

Gleason scale (5 + 1), what is the predominant pattern:

Male, urinate often, after only 1 beer, palpable prostate, 5ng/ml PSA:

Fallopian tube epithelium:

Rupture of mucinous tumor of ovary into peritoneum and with mucin deposits is called:

Hydatidiform mole proceed choriocarcinoma in:

Produce estrogen, may give endometrial cancer and breast cancer:

Stage I adenocarcinoma of the uterus:

Most likely tuberculosis:

Diagnosis of ovarian tumor lined by tall columnar cells. Histology of fallopian tube cells:

Malignant serous tumor of ovary typically spreads to:

The risk of developing endometrial carcinoma in atypical hyperplasia with cellular atypia is:

Sharply circumscribed, firm gray-white mass with a characteristic whorled cut surface present in the myometrium of the uterus is most likely:

In which of the following lesions hydropic villi may embolize to distant organs, such as lungs or brain. Emboli do not constitute true metastases and may actually regress spontaneously:

How many choriocarcinomas arise in complete hydatidiform moles:

Which of the clinical variants of malignant melanoma begins with the vertical growth phase without an obvious radial growth phase?

The definitive diagnosis of malignancy in pheochromocytomas is based exclusively on:

Following characteristics: “tumor composed of polygonal to spindle-shaped cells and their supporting cells, compartmentalized into small nests by a rich vascular network. Polygonal to spindle-shaped cells are chromogranin A positive and synaptophysin positive. “most likely corresponds to:

Which of the clinical variants of malignant melanoma begins with the radial growth phase and stays in situ only for months

Malignant melanoma that invades papillary dermis but does not fill it corresponds to

Which of the following clinical variants of malignant melanoma develops in old persons on sun-damaged facial skin and grows very slowly for years before the tumor starts to metastasize

In which of the following tumor satellite or intratransit metastases to skin can be found

Malignant melanoma which stays in situ and grows radially for several years, before it starts to spread vertically. Which type?

Malignant melanoma. Grows vertically directly, without radial spreading, the most aggressive form.

Caucasian male had over 150 pigmented nevi on trunk and arms. Most were 6 mm in diameter, some over 10 mm and various chess of brown color. Family history of melanoma. What is the most correct statement?

Which of the clinical variants of malignant melanoma begins with vertical growth phase and has poorest prognosis

Verruca vulgaris is mostly found in:

Peak incidence of follicular carcinoma

Histologic examination revealed cords and islands of malignant cells with hyper chromatic nuclei, and peripheral tumour cell nuclei palisading, embedded in a fibrotic or mutinous stroll matrix. The most likely diagnosis is:

Figo staging is used for