Endocrine overview and intro

Which of the following are NOT one of the main hormone groups

Which hormone groups have cell surface receptors?

What makes up regulated secretion?

Precursors of amino acid derived hormones

Hormones derived from tyrosine

The thyroid hormone has 2 forms T4 and T3. After being converted in the liver or target cells what form does it take?

What form of thyroid hormone is mostly bound to thyroxin binding globulin for transport in the blood?

What are some examples of catecholamines?

What is the best way to degrade catecholamines?

Catecholamines can be synthesized from either

What type of hormones are derived from cholesterol (released in the blood as lipid droplets coated with protein)?

What hormones cannot be stored in vesicles once synthesized?

What are eicosanoids derived from?

Which secreting cell contains an extensive rough ER with well developed golgi bodies?

Negative feedback loops are more common to regulate hormones as it maintains homeostasis

Hormones are present at high concentrations in circulation

Which is NOT a factor that affects the hormone delivered to a target?

The binding of a hormone to the receptor results in a conformational change in the receptor resulting in a effect within the target cell

If a hormone receptor has high affinity and specificity how many receptors are needed?

Which receptor binder binds to the receptor for a particular ligand and mimics its action?

Which receptors typically generate second messengers which alter the activity of other molecules, usually enzymes within the cell?

Which receptors alter transcriptional activity of responsive genes?

What are examples of second messenger systems?

Which hormones are inactivated and made water soluble by removal/reduction/oxidation of side chains and conjugation with gluconate or sulfate?

Which hormones are deactivated and made water soluble by deionation, deamination and decarboxylation (sometimes conjugation)

Which hormones bound to receptors are internalized and degraded by the cell?

Which hormones are degraded after H-R complex binds to DNA?

Which hormones have the longest halflife

Which hormones have the shortest half life

Which glands have no ducts with secretions usually transported via circulatory?

Where would you expect cord arrangement?