Check for Understanding (Paroxetine)

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Check Your Understanding of Paroxetine

Test your knowledge on Paroxetine, a commonly prescribed SSRI, with this comprehensive quiz. Whether you are a healthcare professional, a student, or simply interested in learning more about this medication, this quiz will help reinforce your understanding.

21 thought-provoking questions
Multiple choice format for ease of answering
Track your progress and improve your knowledge about Paroxetine

21 Questions5 MinutesCreated by LearningLeaf24

Paroxetine is a SSRI that acts on what neurotransmitter

Norepinephrine

Glutamate

Dopamine

Serotonin

Paroxetine has a broad indication in addition to depression and anxiety that includes

OCD

PTSD

Panic disorders

All of the above

It is the mechanism of action of Paroxetine

Paroxetine blocks the release of serotonin in the presynaptic vesicles

Paroxetine blocks the binding of serotonin to its receptors

Paroxetine blocks the serotonin gate to regulate serotonin reuptake

Paroxetine blocks the presynaptic neuron from producing serotonin

Bioavailability of Paroxetine is low due to

Extensive first-pass metabolism

Easy metabolism in the liver

Fast disintegration upon intake

Drug to drug interactions

Peak plasma concentration of Paroxetine is achieved in

3 hours

5.2 hours

4 hours

30 minutes

Metabolism of Paroxetine is in the

Presynaptic neurons

Kidneys

Liver

Small Intestines

Excretion of Paroxetine is both in the urine and feces

~20% urine and ~80% feces

~64% urine and ~36% feces

~90% urine and ~5% feces

25% urine and 75% feces

Recommended starting dose of Paroxetine

20 mg

5 mg

60 mg

Maximum daily dose of Paroxetine

80 mg

50 mg or 60 mg

70 mg

40 mg

Discontinuation of Paroxetine is possible

It can be abrupt like other medications

It should be tapered down by a daily dose of 10 mg

It can be discontinued after 1 week

It is based on patient's preference

Paroxetine is indicated to the following patients

Children

Adolescents

Pregnant patients

Adults

Paroxetine can be prescribed in patients with mania

It should be given to adult manic patients

It should not be given at all

It should be used with caution

None of the above

Paroxetine in pregnancy may increase this risk in newborn

Persistent Pulmonary hypertension in newborn

Autism and ADHD in children

Congenital Heart Disease

Juvenile diabetes

Most common side effects of Paroxetine

Sea sickness-like condition

Nausea

Pulmonary conditions

Vertigo

This society recommends SSRIs as first line therapy for GAD, OCD, panic disorder, social anxiety disorder and for pharmacotherapy of core symptoms of PTSD

American Psychiatric Association

NICE, UK

Anxiety Disorders Association of Canada

Philippine Academy of Family Physicians

The dose range of Paroxetine

10 mg - 60 mg

20 mg - 60 mg

10 mg - 40 mg

5 mg - 60 mg

The half life of Paroxetine

20 hours

26 hours

24 hours

18 hours

The only drug of its class indicated for all five anxiety disorders in addition to major depressive disorder, for OCD, panic disorder, social anxiety disorder, GAD and PTSD

Escitalopram

Sertraline

Paroxetine

Duloxetine

Precautions of Paroxetine

Suicidal thoughts

Akathisia

Serotonin syndrome

All of the Above

Paroxetine cannot be co-administered with

MAO-I

Thioridazine

Pimozide

All of the above

Check for Understanding (Paroxetine)

Check Your Understanding of Paroxetine

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