Bio334 basic concepts - Each question can have multiple correct answers
Bio334 Flux Balance Analysis Quiz
Test your knowledge of flux balance analysis and its fundamental concepts with this engaging quiz designed for students and educators in the field of biological sciences. Whether you're reviewing for an exam or just want to reinforce your understanding, this quiz covers key principles and truths about metabolic networks.
- Multiple-choice questions
- Instant feedback on your answers
- Learn more about essential reactions and flux variability analysis
What are the fundamental assumptions of flux balance analysis?
Metabolites are in steady state
Metabolites are accumulated to be converted optimally into biomass later
Cells use metabolism to maximize growth
Cells try to use as few resources as possible
For the network in Fig 1, select the answers you know are true
The flux through reaction 1 is 1 mmol/g/hr
A flux of 10 mmol/g/hr in reaction 1 would require a flux of 20 mmol/g/hr in reaction 4
A flux of 10 mmol/g/hr in reaction 1 would require a flux of 5 mmol/g/hr in reaction 4
Metabolite B cannot enter or leave the system
Which of these reaction classes are artificial, I.e. They have no counterpart in the real world?
Internal reactions
External reactions
Biomass reactions
Transport reactions
Minimal medium or minimal environment refers to:
An environment containing glucose only
An environment which offers a single source of carbon, nitrogen, phosphorus, and extra things required for growth
An environment which does not contain glucose, but everything else required for growth
An environment with a very small amount of glucose, phosphorus, nitrogen, etc
Which of the following statement(s) about essential reactions is(are) true:
Essential reactions are always external reactions.
Shutting down an essential reaction opens a new path to optimize the objective reaction.
Essential reactions always need to be active for growth to occur.
Active reactions are synonymous for essential reactions.
Which of the following statements about flux variability analysis are true?
Essential reactions are inflexible
The flexibility of a network decreases with the growth rate
It gives the maximum and minimum flux value a reaction can achieve
Non-essential reactions are blocked
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