RESIDENCY EXAM INFLAMMATION
1) In acute inflamation
Predominant cell is neutrophils
Onset :minute to hours
Systemic signs are less
Predominant cell is macrophages
Neo vascularization occur
2)Exudate formed :
In acute inflammation
Due to increased osmotic pressure
Due to increased hydrostatic pressure
In chronic inflation
Due to vesodialation
3) exudate :
Spesific gravity 1.00
Contain neutrophil
Plasma protein – pnly albumin
Contain fibrinogen
Contain RBC
4)swelling in acute inflamation occur due to
Increased vascular permeability
Accumulation of exudate
Neoplastic changes
Accumulation of neutrophil
New tissue formation
5) in acute inflamation
Transient veso constriction occur
Vesodialation occur
Increase vascular permeability
Increase CRP
High ESR
6)fate of acute inflamation
Chronic inflamation
Resolution
Dysplastic changes
Scar formation
Healing by neo vascularization
7)following are the cell of acute inflamation
Macrophages
Neutrophil
Activated macrophage
B lymphocyte
Eosinophil
8) chronic inflamation:
Oedema present
Exudate present
Transudate presrnt
Tissue destruction
Vascular changes
9) in acute inflamation vascular changes occur
Capillary first
Artery first
Vein first
Lately
Arteriole first
10) Hall mark of chronic inflamation
A) vascular changes.
B) tissue destruction
C) neutrophils
D) eosinophil.
E) fibrosis
12) Enzyme released from activated macrophage
Neutral protease
Acid hudrolase
Elastase
Plasminogen activator
Laipase
18) after phagocytes micro organisms are killed by
H2O2
Lactoferrin
Myeloperoxidase
Hydrochloride
Defensin
20) which are the pre formed inflamatory mediators
Histamin
Lysosomal enzyme
NO
Cytokines
Prostaglandin
26)NO :
Synthesized from molecular oxygen
Synthesized from I-arginine
Ca required for synthesis
Required nitric oxide synthase
Released from endothelial cell
27)macrophage
Play central role in chronic inflamation
Can synthesis NO
Control granulopoiasis
Antigen presenting cell
Produce IL -1
30)CRP
Produce in liver
IL-6 upregulate its synthesis
Activate complement by classical pathway
Antigen spesific
E)late indicator of acute inflammation
33)following which are granulomatous bacterial diseases
Tuberculosis
Gonorrhea
Histoplasmosis
Leprosy
Shistosomiasis
34) granuloma is composed of –
Macrophage
T lymphocyte
Modified activated macrophage
Modified B lymphocyte
Neutrophil
35)granulomas in TB
Heal by fibrosis
Always contain giant cell
Are discreet in nature
Always show central caseation
Made of epithelioid cell
36) following cells are involved in acute inflamation
Lymphocyte
Neutrophil
Endothelium of blood vessel
Epithelioid cell
Mast cell
38) Giant cell are found in the pathological lesion associated with following diseases
Actinomycosis
Primary biliary cirrhosis
Lepromatus leprosy
Schistosomiasis
Hodgkin diseases
40) Cytokines
Released from endothelial cell
Cause local endothelial activation
Released from basophil
TNF
NO
42) chronic inflamatory cells asociated with arthritis
Eosinophil
Mast cell
Macrophage
Neutrophil
Lymphocyte
44) proliferative inflamation :
Transudate formation
Weeks to month
Granulomatous tissue
Tissue destraction minimum
Exudate formation
45) Transudate :
Occur due to increase hydrostatic pressure
Found in liver cirrhosis
Found in acute inflamation
Neutrophil present
Albumin oresent
47) inflamation
Is a host defense
Sometime harmful to human body
Autoimmune is is a example
Occur with in minute
Occur in hair
48)exudate :
Dilute irritant or harmful substance
Act as potent media for bacterial growth
It help phagocytosis
Ph is low
Contain fibrin
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