An infant born to a 40-year-old female has a flat face, up-slanting palpebral fissures, a small mouth and a single palmar crease. On physical examination, the infant has a blowing holosystolic murmur heard best along the sternal border. Of the chromosomal

An infant born to a 40-year-old female has a flat face, up-slanting palpebral fissures, a small mouth and a single palmar crease. On physical examination, the infant has a blowing holosystolic murmur heard best along the sternal border. Of the chromosomal abnormalities listed below, which is most likely to have caused the clinical findings described?

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