Part 3 Immunology(100-149) prof. Keit vanseth

A highly detailed illustration of the human immune system, showcasing various immune cells like macrophages, T cells, and antibodies, with a vibrant background depicting an interacting pathogen.

Immunology Mastery Quiz

Test your knowledge of immunology with our comprehensive quiz! With 50 carefully crafted questions, you'll explore key concepts, mechanisms, and terminology related to the immune system.

This quiz is perfect for students, educators, and professionals looking to refresh their understanding of immunology. Topics include:

Innate and adaptive immune responses
Immunoglobulin structure and functions
Complement pathways
Autoimmune diseases

50 Questions12 MinutesCreated by LearningCellar475

100. What's a specific term for a bacterial or other foreign protein that initiates antibody production by the body?:

σ� Peptide

σ� MHC II molecule

σ� Complement

σ� Antigen

101. Which of the following bacteriocidal mechanisms is oxygen dependant?:

σ� NADPH oxidation

σ� Defensins

σ� Hydrolytic enzymes

σ� Lactoferrin

102. Pepsin cleaves what region of immunoglobulin?:

σ� Heavy chain

σ� Light chain

σ� Hinge region

σ� Heavy chain and Light chain

103. Papain cleaves what region of immunoglobulin?:

σ� Heavy chain

σ� Light chain

σ� Hinge region

σ� Heavy chain and Light chain

104. Biological properties of C5a are:

σ� Chimotactic activity

σ� Anaphylactic much potent

σ� Attract and activate PMN

σ� All answers

105. Which of the following binds to an Fc receptor on mast cells and basophils?:

σ� IgA

σ� IgM

σ� IgE:

σ� IgG

106. Which of the following is a β structural chain in class I MHC?:

σ� β1

σ� α1

σ� α2

σ� β2 –microglobin

107. Which of the following is NOT a structural chain in class II MHC?:

σ� α1

σ� α2

σ� α3

σ� β 1

108. The initial complement component that is bound by complement-fixing antibodies is:

σ� C1q

σ� C1s

σ� C3b

σ� C5a

109. Molecule binding to their receptors at high affinity :

σ� Cytokines

σ� Antibody

σ� Antigen

σ� All answer

110. Which of the following components of the innate immune system involves the release of histamine?:

σ� Neutrophil

σ� Eosinophil

σ� Macrophage

σ� Tissue mast cell

111. Which of the following components of the adaptive immune system secretes immunoglobulin (Ig)?:

σ� Activated B cell (plasma cell)

σ� CD4+ activated T cell

σ� CD8+ cytotoxic T cell (CTL)

σ� Resting lymphocytes (B cell, T cell)

112. The region of immunoglobulin term: Binds to various cellular receptors and to complement:

σ� Fab region

σ� Fc region

σ� Light chain

σ� Heavy chain

113. The C5 convertase of Classic and Lectin pathway is:

σ� C4b2a4b

σ� C4b2b3a

σ� C4b2a3b

σ� C3bBb3b

114. The C5 convertase of Alternative pathway is:

σ� C4b2a4b

σ� C4b2b3a

σ� C4b2a3b

σ� C3bBb3b

115. The Complement that gives Anaphylotoxin much potent is:

σ� C4a

σ� C5a

σ� C2b

σ� C3a

116. Which of the following immunoglobulin is first synthesized in an immune system to response an pathogen?:

σ� IgM

σ� IgA

σ� IgG

σ� IgE

117. Which of the following statement is related to IgG physiology in humans?:

It is confined to the bloodstream, giving the host protection against blood-borne pathogens.

It can be arranged to resemble a pentamer of five distinct immunoglobulin molecules.

σ� Opsonisation through FcR on macrophages occurs with IgG2 and IgG4.

σ� IgG crosses the placental barrier, and thereby provides passive immunity to the fetus.

118. Which of the following statements about leukocyte function is false?:

σ� Leukocytes are cells of the immune response.

σ� Neutrophils phagocytose pathogens .

σ� Eosinophils kill parasites.

σ� Eosinophils release histamine .

119. Microbial Fragment Vaccines is used to prevent the diseases below, EXCEPT:

σ� Polio

σ� Haemophilus influenzae B

σ� Hepatitis B virus

σ� Neisseria meningitides

120. The family of Hepatitis B virus is named:

σ� Hepadnavirus

σ� Flavivirus

σ� Retrovirus

σ� CMV

121. Clinical abnormalities of the Immune system can result from the activities below:

σ� Neutrophils kill bacteria

σ� Abnormal lymphocyte proliferation

σ� Plasma cells secrete antibody

σ� T cell secrete cytokine

122. Which of the following is NOT a major feature (characteristic) of the adaptive immune system?:

σ� Specificity

σ� Diversity

σ� Memory

σ� Improvement

123. The following statement are function of immune system, EXCEPT:

σ� Can be facilitated by antibodies

σ� Mediated the humoral and cellular response

σ� Facilitated by T-cells

σ� Allow pathogen to infect the bod

124. Which of the followings are TRUE regarding an Immune response:

σ� The T3 complex is signal to the cell's interior to recognize antigen

σ� The T8 support MHC II in cytotoxic reactions

σ� The T4 support MHC class I in helper reactions

σ� T4 The secrete antibody

125. The component of immune system that can cause fever is :

σ� Complement

σ� Immunoglobulin

σ� T lymphocytes

σ� Macrophage

126. In a chronic infection of Hepatitis B, the typical serologic course are :

σ� HBsAg

σ� HBcAb

σ� HBsAb

σ� HBsAg and HBcAb

127. Identity the phagocytic cells that have Toll like Receptor on their membrane:

σ� Macrophage

σ� Eosinophil

σ� Basophil

σ� Neutrophil

128. The disease below can cause by autoimmune:

σ� Hepatitis

σ� Thalassemia

σ� Cancer

σ� SLE

129. The following cells are proliferated from myloid progenitor :

σ� B cells

σ� TH1

σ� Lymphocytes

σ� Dendritic cells

130. Intracellular pathogen is presented to the Tc by:

σ� MHC I

σ� MHC II

σ� Lymphocytes

σ� TH

131. Tumor Necrose Factor (TNF) produce by:

σ� Neutrophil

σ� Macrophage

σ� Tc

σ� Macrophage and Tc

132. Platelets can produce by those organs:

σ� Liver

σ� Spleen

σ� Bone marrow

σ� Thymus

133. Myeloid cells below lived in tissue:

σ� Macrophage

σ� Neutrophil

σ� Lymphocyte

σ� Basophil

134. Biological effect of Complement C5a is:

σ� Neutrophil activation

σ� Opsonisation

σ� Inflammation

σ� Phagocytosis

135. Biological effect of Complement C2b is:

σ� Anaphylaxis

σ� Opsonisation

σ� Edema

σ� Phagocytosis

136. Biological effect of Complement C3a is:

σ� Anaphylaxis

σ� Opsonisation

σ� Edema

σ� Phagocytosis

137. Biological effect of Complement C4a is regulated by:

σ� Factors H & I

σ� C3-INA

σ� C4-BP

σ� Factor I

138. The Complement that produce anaphylactic much more potent is:

σ� C2b

σ� C5a

σ� C4a

σ� C3a

139. Which immunoglobulin is used to test for blood group:

σ� IgG

σ� IgE

σ� IgA

σ� IgM

140. Which immunoglobulin is used to produce vaccine:

σ� IgG

σ� IgE

σ� IgA

σ� IgM

141. The fragment of Antigen is called:

σ� Immunogen

σ� Hapten

σ� Antigenic determinant

σ� Immunoglbulin

142. How many receptors for antigen on the surface of T lymphocyte:

σ� 1

σ� 2

σ� 4

σ� 10

143. How many receptors for antigen on the surface of B lymphocyte:

σ� 1

σ� 2

σ� 4

σ� 10

144. Where is the variable region of Immunoglobulin?:

σ� VL

σ� CL

σ� CH2

σ� CH3

145. The function of MHC class II is:

σ� Recognized by CD4

σ� Recognized by the CD8

σ� Presentation Ag to Th cell

σ� Unable to carry antigen fragment

146. The function of LGL cell is:

σ� Response to bacteria infection

σ� Respose to tumor cells

σ� Response to antibody

σ� Kill pathogen

147. Which cells secreted most cytokine in innate immune:

σ� T lymphocyte

σ� B lymphocyte

σ� Macrophage

σ� Plasma cell

148. The answers below are characteristic of antigen, EXCEPT:

σ� Contain paratopes

σ� Contain epitopes

σ� Are toxin

σ� React with antibody

149. The following answers are true for IgM antibodies, EXCEPT:

σ� Fix complement

σ� Anti infectious

σ� Cause of allergy

σ� Pentametric form

Part 3 Immunology(100-149) prof. Keit vanseth

Immunology Mastery Quiz

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