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Clinical biochemistry L6

A detailed anatomical illustration of the human liver, highlighting bilirubin metabolism and liver fun<wbr>ctions, featuring elements such as enzymes and biochemical pathways, in a bright and educational style.

Clinical Biochemistry Quiz

Test your knowledge on clinical biochemistry with our engaging quiz! Explore various aspects of bilirubin metabolism, liver function tests, and nitrogen balance.

Perfect for students and professionals in the medical field.
Enhance your understanding of liver-related conditions and biochemical markers.

14 Questions4 MinutesCreated by AnalyzingLiver47

4.________ is a general condition that results from abnormal metabolism or retention of bilirubin.

Jaundice

Pre-hepatic jaundice

Hepatic jaundice

Post hepatic jaundice

5. _________ is the result of acute or chronic hemolytic anemias.

Jaundice

Pre-hepatic jaundice

Hepatic Jaundice

Post hepatic jaundice

6._________ includes disorders of bilirubin metabolism and transport defects.

Jaundice

Pre-hepatic jaundice

Hepatic jaundice

Post hepatic jaundice

7.________ includes disorders of bilirubin metabolism and transport defects.

Jaundice

Crigler-Najjar syndrome

Hepatic jaundice

Post hepatic jaundice

8. _________ is caused by a defect in the transport of bilirubin from plasma albumin into the hepatocyte.

Gilbert’s disease

Crigler-Najjar syndrome

Hepatic jaundice

Post hepatic jaundice

9. ________ The last step in the hepatic processing of bilirubin is the post-conjugation step of excretion of the bilirubin-glucuronide from the hepatic microsomes into the canaliculi.

Gilbert’s disease

Crigler-Najjar syndrome

Hepatic jaundice

Dubin-Johnson syndrome

10.__________ is generally caused by biliary obstructive disease resulting from spasms or strictures of the biliary tract, ductal occlusion by stones, or compression by neoplastic disease.

Gilbert’s disease

Crigler-Najjar syndrome

Hepatic jaundice

Dubin-Johnson syndrome

Post-hepatic jaundice

11. Concentrations and Changes in Concentration of Bilirubin and Its Metabolites in Healthy Person and Those with Jaundice

- What pathological conditions that cause presence of Bilirubin in urine?

Hepatocellular disease

Dubin-Johnson syndrome

Posthepatic obstructive jaundice

All answers above

13. Change of Serum Analyte with Disease: Enzymes Which pathological condition that causes the highest of GGT level?

Cirrhosis

Reye’s syndrome

Hepatomas

Cholestatic disease

12.

- Liver-function tests are generally used to identify liver disease in the absence of
jaundice or when the jaundice is the result of hemolytic disease and the existence of
complicating liver disease is suspected.
- Based on capacity of liver, hepatocellular damage and obstruction, liver function
tests are classified as the following:

Test based on excretory capacity of liver (Indocyanin green, Phenoldulfon-phthalein, BSP)

Test based on detoxifying capacity of liver (hippuric acid, the liver's ability to metabolize drugs to changes in serum concentration of the parent drug or its metabolite)

Test based on synthetic capacity of liver (Total protein, Albumin, Prothrombin time, serum cholesterol)

Test based on metabolic capacity of liver (Serum ammonia)

Tests used for indicating hepatocellular damage and obstructive liver disease (ALT, AST, ALP, GGT, N5T)

2. Nitrogenous Balance:

1. Intake = output : N equilibrium______

An increase in the total body pool of protein

Normal state in an adult

A net loss of body protein

2. Nitrogenous balance

2. Intake > output : positive _______

An increase in the total body pool of protein.

Normal state in an adult

A net loss of body protein

2. Nitrogenous balance:

3.N balance intake < output: negative N balance_______

An increase in the total body pool of protein

Normal state in an adults

A net loss of body protein

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