Oral Pharmacology, Prof. Tuy Thel(121-180)

121.          The short action of certain barbiturates is due to?

122.          The most important therapeutic measure to be taken in a case of barbiturate poisoning is to?

123.          A patient with xerostomia complains that he has to sip water when chewing food. Which salivary gland(s) is most likely responsible for the lack of lubrication?

124.          The major stimulator of respiration is?

125.          The majority of nitrous oxide is eliminate from a patient's circulatory system through the?

126.          Which of the following nerves are anesthetized by an infraorbital nerve block? 1. Zygomatico-temporal. 2. Palpebral. 3. Zygomatico-facial. 4. Lateral nasal. 5. Labial.

127.          The left infraorbital nerve block anaesthetizes?

128.          Intake of acetylsalicylic acid by a patient will result in ?

129.          Acetylsalicylic acid may be safely used as an analgesic in patients who?

130.          The following drugs relieve pain EXCEPT?

131.          Which of the following is NOT associated with the administration of acetylsalicylic acid?

132.          Tetracyclines ? 1. Have no side effects. 2. May increase susceptibility to superinfections. 3. Are safe to use during pregnancy. 4. Have a wide spectrum of antibacterial activity.

133.          Which of the following is NOT a sign of congenital heart disease?

134.          A therapeutic advantage of penicillin V over penicillin G is?

135.          A patient with congestive heart failure may have? 1. epistaxis. 2. Shortness of breath. 3. rhinophyma. 4. Pitting edema of the ankles.

136.          Acetaminophen in therapeutic doses? 1. Retards platelet function. 2. Has strong anti-inflammatory properties 3. produces CNS stimulation. 4. Has antipyretic properties.

137.          Short-acting barbiturates are metabolized mainly in the?

138.          The principal difference between potassium,procaine and benzathine salts of penicillin G is their?

139.          Which of the following is a local anesthetic subject to inactivation by plasma esterases?

140.          Procaine differs from lidocaine in that?

141.          Which of the following local anesthetics would be expected to produce a sensitization reaction in a patient allergic to lidocaine? 1 . Mepivacaine 2 . Tetracaine 3 . Procaine 4 . Prilocaine 5 . Dibucaine

142.          another ester vs. Amide type identification question. Lidoccaine is an amide, thus other amides will be crossallergenic - mepivacaine, prilocaine and dibucaine are the other amides listed. Procaine and tetracaine are esters and will not be cross-allergenic. The hydrolysis of procaine occurs mainly in the?

143.          Which of the following is local anesthetic subject to inactivation by plasma esterases?

144.          The activity of procaine is terminated by?

145.          All of the following factors are significant determinants of the duration of conduction block with amide-type local anesthetics EXCEPT the?

146.          Which of the following is contraindicated for a patient who had an allergic reaction to procaine six months ago?

147.          Bupivacaine (Marcaine ) has all of the following properties relative to lidocaine (Xylocaine ) EXCEPT bupivacaine?

148.          Amide-type local anesthetics are metabolized in the?

149.          The duration of action of lidocaine would be increased in the presence of which of the following medications?

150.          Severe liver disease least affects the biotransformation of which of the following?

151.          A patient has been given a large volume of a certain local anesthetic solution and subsequently develops cyanosis with methemoglobinemia. Which of the following drugs most likely was administered?

152.          Use of prilocaine carries the risk of which of the following adverse effects?

153.          The most probable cause for a serious toxic reaction to a local anesthetic is?

154.          High plasma levels of local anesthetics may cause?

155.          Unfortunately, you injected your lidocaine intra-arterially. The first sign of lidocaine toxicity that might be seen in the patient would be?

156.          The first sign that your patient may be experiencing toxicity from too much epinephrine would be?

157.          Therapeutic doses of morphine administered intramuscularly may produce? 1. constipation. 2. euphoria. 3. Mental clouding. 4. dysphoria.

158.          Cardiovascular collapse elicited by a high circulating dose of a local anesthetic may be caused by?

159.          The most serious consequence of systemic local anesthetic toxicity is?

160.          Hypotensive shock may result from excessive blood levels of each of the following local anesthetics EXCEPT?

161.          Which of the following anesthetic drugs produces powerful stimulation of the cerebral cortex?

162.          Local anesthetics block nerve conduction by?

163.          Which of the following is true regarding the mechanism of action of local anesthetics?

164.          Local anesthetic agents prevent the generation of nerve impulses by?

165.          Local anesthetics interfere with the transport of which of the following ions during drug-receptor interaction?

166.          A local anesthetic injected into an inflamed area will NOT give maximum effects because?

167.          Which of the following statements are true regarding onset, degree and duration of action of local anesthetics? 1. The greater the drug concentration, the faster the onset and the greater the degree of effect 2. Local anesthetics block only myelinated nerve fibers at the nodes of Ranvier 3. The larger the diameter of the nerve fiber, the faster the onset of effect 4. The faster the penetrance of the drug, the faster the onset of effect

168.          A dentist administers 1.8 ml of a 2 % solution of lidocaine. How many mg of lidocaine did the patient receive?

169.          Three ml of a local anesthetic solution consisting of 2% lidocaine with 1:100,000 epinephrine contains ho w many milligrams of each?

170.          The maximum allowable adult dose of mepivacaine is 300 mg. How many milliliters of 2% mepivacaine should be injected to attain the maximal dosage in an adult patient?

171.          A recently introduced local anesthetic agent is claimed by the manufacturer to be several times as potent as procaine. The product is available in 0.05% buffered aqueous solution in 1.8 ml. cartridge. The maximum amount recommended for dental anesthesia over a 4- hour period is 30 mg. The amount is contained in approximately how many cartridges?

172.          According to AHA guidelines, the maximum of carpules of local anesthetic containing 1:200,000 epinephrine that can be used in the patient with cardiovascular disease is?

173.          Which penicillin has the best gram-negative spectrum?

174.          What are symptoms seen during allergic reactions to penicillins? 1.dermatitis2.stomatitis 3.bronchoconstriction 4.cardiovascular collapse"

175.          Aplastic anemia is associated with...?

176.          Liver damage or hepatotoxicity is associated with...?

177.          For treating most oral infections, penicillin V is preferred to penicillin G because penicillin V?

178.          The sole therapeutic advantage of penicillin V over penicillin G is?

179.          Q180/ . Which of the following penicillins is administered ONLY by deep intramuscular injection?

180.          The principal difference among potassium, procaine and benzathine salts of penicillin G is their?