Endo N1 2020/21

Mark the CORRECT answer about acromegaly:

When there is NO need to increase the substitution dose of glucocorticoids in patient with Addison’s disease?

What are the typical symptoms of monotropic TSH deficiency? (tertiary hypothyroidism, caused by decreased hypothalamus TRH secretion)

The most common cause of Addison’s disease:

A 78 year old woman is referred to the Endocrinology Outpatient Clinic due to low TSH: 0,05 µIU/ml(0,270-4,200) FT4: 1,66 ng/ dl(0,93-1,70), FT3: 4,6 (2,00-4,40) pg/ml. She complaints of diarrhea which began 3 months ago and reports 4 kg of weight loss in the last 4 weeks. She has a history of smoking and had a prophylactic contrast CT of the chest 4 months ago which did not reveal any abnormalities. What would be the initial diagnosis and what studies would you perform to determine the etiology of the hormonal abnormalities?

In primary hyperaldosteronism which laboratory abnormality can occur?

The most common cause of primary hypothyroidism in iodine- sufficient area:

What medications may we use to relieve symptoms of thyrotoxicosis?

Which imaging studies should be done in the suspicion of primary hyperparathyroidism?

The increased mortality in Cushing syndrome is caused by:

Which of the following disorders are common to MEN1 and MEN2 syndromes?

37-years-old male patient reported to the emergency department complaining of paresthesias of the extremities and tongue. In physical examination you find positive Trosseau and Chvostek's signs. Which underlying disorder is the most probable cause?

The most common thyroid cancer in non-iodine deficiency region is:

In which of the following conditions we can observe pallor of the skin together with high blood pressure values?

Which disease is more likely to occur with Hashimoto's disease?

What are the symptoms of monotropic ACTH deficiency?

True statement about TSH-oma (thyrotropinoma) is:

Dexamethasone Suppression Test (with high dose of dexamethasone) helps to distinguish patients with:

A common complication of radio-iodine therapy in patients with hyperthyroidism:

Mark the correct statement:

A 23-year-old woman came to the Endocrinology Outpatient Clinic because she has been observing galactorrhea for 3 months. Laboratory tests showed a PRL concentration of 300 ng/ml (N: 4,79 - 23,30). The presence of a focal lesion (5mm) was confirmed by pituitary MRI. What will be the best treatment for the patient?

What are the possible complications of thyroidectomy?

Which of the following tests would be most helpful in confirming the diagnosis of Cushing's syndrome?

What are the treatment options in hyperthyroidism in Graves disease:

Laboratory findings characteristic for secondary hyperparathyroidsm are:

The symptom which is not due to hypothyroidism is, choose one answer:

How to recognize secondary hypothyroidism in laboratory tests?

The patient diagnosed with Addison's disease you will treat with:

Which of the following hormone is not secreted by pituitary?

Mark a correct statement about the follow-up after thyroidectomy due to differentiated thyroid cancer:

31. You are an endocrinologist at outpatient clinic. A 32-year-old woman with hypertension and impaired glucose tolerance was referred to you by general practitioner with a suspicion of acromegaly. She claims that her appearance has changed over last 2 years. She has noticed thickening of the jaw, nose and zygomatic arches, over two years she had to change shoe size every 6 months. Also she has been suffering from chronic headaches, muscle pain and night sweating. Ten years ago her father was diagnosed with pituitary macroadenoma and underwent transphenoidal surgery. Beside hypotensive treatment she doesn’t take any medications. In physical examination, beside abnormalities mentioned above, you find: enlargement of the tongue and bitemporal hemianopsia. What laboratory test you should order first?

Mark a correct statement about Graves Orbitopathy (thyroid eye disease):

Which of the following features occurs in Cushing's Syndrome, but is not a feature of metabolic syndrome?

51-year-old man was admitted to outpatient clinic due to hypercholesterolemia. He reported weight gain (8 kg in 6 months), constipation, dry skin and hair loss. In lab. tests: TSH 17,90 uIU/ml (normal 0,4-4,0), fT3 1,11 pg/ml (2-4), fT4 0,51 ng/dl (normal 0,8-1,7) What is the test and treatment You choose?

Which of the following laboratory abnormalities is the most typical in patients with Cushing's syndrome?

Which of the following is NOT a cause of hyperprolactinemia?

What laboratory abnormalities may you expect in patient with Addison’s disease?

In patient with suspicion of Addison’s disease cortisol level and ACTH levels are respectively: Morning: Cortisol 6,0 ug/dl (normal range 6-19), ACTH 120,0 pg/ml (normal range 7-50). Evening: 1,4 ug/dl and 100 pg/ml respectively. What test should you do next to confirm the diagnosis finally?

The most common cause of endogenous hypercortisolism in the adults is:

When do you suspect Sheehan's syndrome?