GENCOUN510- Chapter 2 Prior Knowledge Quiz

When a cell is instructed to die, it is called

Programmed cell death

Apoptosis

Both

Neither

What is the main cause of numerical chromosome abnormalities in humans?

Homologous recombination

Non-homologous recombination

Mitotic nondisjunction

Meiotic nondisjunction

Currently, which of the following is considered to be the number of protein-coding genes in the human genome?

20,000

25,000

50,000

200,000

Which of the following is NOT true for LINE sequences?

LINE stands for long interspersed nucleosome elements

Together they are called the L1 family

They are up to 5 kb in length

There are approximately 850,000 copies per genome

How many different types of human chromosomes are there?

The Human Genome consist of

3.3 million base pairs of DNA

3.3 billion base pairs of DNA

3.3 trillion base pairs of DNA

None of the above

Meiosis is the process by which diploid cells give rise to haploid gametes.

True

False

The Meiotic reduction division, where the chromosome number is reduced by half, occurs in

Meiosis I

Meiosis II

Both

Neither

The number of copies of these repeats are correlated with life expectancy and longevity.

Centromeres

Kinetochores

Telomeres

Chromatin

Which is NOT true for DNA?

Nucleotides are composed of a base, a phosphate, and a sugar moiety

Nucleotides are polymerized together in a chain held together by 3’-5’ phosphodiester bonds

Bases consist of pyrimidines (thymine and cytosine) and purines (adenine and guanine)

Nucleotides are composed of a five-carbon sugar, deoxyribose

What percent of the human genome is made up of clustered repeated sequences?

Less than 1%

1-2%

5-10%

Over 10%

During S phase, each chromosome is duplicated and results in

A single DNA molecule

Two sister chromatids

Two nonidentical copies of the linear DNA

Protein

Which of the following is NOT part of the histone octamer?

H2A

Which of the following does NOT accurately represent how long a typical cell is in a particular phase of the cell cycle?

M phase 1-2 hours

G1 phase 10-12 hours

S phase 1-2 hours

G2 phase 2-4 hours

Which of the following contributes to the structure called a nucleosome?

20- to 60-bp of DNA associated with the histone octamer

140-bp of “spacer” DNA

None of the above contribute to the nucleosome

Estimates are that any two randomly selected individuals will have sequences that are _____ identical.

50%

75%

99.5 to 99.9%

99.999999%

The mitochondrial chromosome:

Does not contain any genes that contribute to the human genome

Is only 1,000 kb in length

Contains only 37 genes

Contributes no protein products important for mitochondria

Select the correct order for Mitosis.

Prophase, prometaphase, metaphase, anaphase, telophase

Telophase, anaphase, metaphase, prometaphase, prophase

Prometaphase, prophase, anaphase, metaphase, telophase

Prophase, prometaphase, anaphase, metaphase, telophase

Of all of the base pairs of DNA in the human genome, what percent actually encodes proteins?

Less than 0.5%

Approximately 1.5%

About 3.5%

Over 5%

GENCOUN510- Chapter 2 Prior Knowledge Quiz

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