Part 4 Immunology(150-199) prof. Keit vanseth

Immunology Mastery Quiz
Test your knowledge of immunology with our comprehensive quiz designed for students and professionals alike. With a focus on key concepts such as phagocytosis, T cells, and antibodies, this quiz will challenge your understanding of the immune system.
Whether you're preparing for exams or just looking to refresh your knowledge, this quiz offers:
- 50 detailed questions
- A variety of topics within immunology
- Instant feedback on your answers
150. The following answers are true for phagocytosis, EXCEPT:
σ� Supported by complement
σ� Opsonisation
σ� Ingest pathogen
σ� NK cell
151. The following activity is indicated T cell cytotoxic:
σ� MHC-II restricted
σ� MHC-I restricted
σ� B cell activation
σ� Epitope presented to CD4
152. Which cell is T helper:
σ� CD8
σ� CD14
σ� CD4
σ� CD15
153. Which cell is Monocyte:
σ� CD8
σ� CD14
σ� CD4
σ� CD15
154. Which cell is Granulocyte:
σ� Basophil
σ� Monocyte
σ� Lymphocyte
σ� Macrophage
155. The following statements are true for Antibodies, EXCEPT :
σ� Fc receptor for complement
σ� Extra domain for IgM
σ� Made of heavy and light chains
σ� Receptors for antigens are monovalent
156. The following statements are true for the antigenic determinant :
σ� Is the combining site of an antibody
σ� Is paratope
σ� Small part of the antigen
σ� Is paratope and Small part of the antigen
157. The basic monomeric Immunoglobulin unit is:
σ� Four polypeptide chains
σ� One of five major classes
σ� Four polypeptide chains and One of five major classes
σ� Synthesized by a T-cell
158. Which of the following are mechanisms for neutrophil phagocytosis:
σ� Azerophilic granules
σ� defensins
σ� Hydrolytic enzymes
σ� Azerophilic granules and defensins
159. Identity the phagocytic cells from the following combinations:
σ� Macrophage and neutrophil
σ� Lymphocyte and eosinophil
σ� Macrophage and eosinophil
σ� Eosinophil and neutrophil
160. Class II MHC proteins are :
σ� Recognized by CD4
σ� Recognized by CD8
σ� Used to participate in helper function
σ� Recognized by CD4 and Used to participate in helper function
161. The function of major histocompatibility complex is:
σ� Degrade T4 and T8 polypeptides
σ� Bind antibody for cytokine secretion
σ� Bind complement for cell lysis
σ� Bind epitope for presentation to T-cells
162. The following statements are true for Class II MHC molecules, EXCEPT :
σ� Able to carry an antigen fragment
σ� Recognized by the CD4
σ� Presented antigen to Tc cells
σ� Used to participate in Th function
163. All of the following are a part of innate immune respond, EXCEPT :
σ� Pathways of complement activation
σ� Natural Killer cells
σ� T cells secrete antibody
σ� Macrophage secrete cytokines
164. All of the following are function of IgG, EXCEPT :
σ� Primary response to antigen
σ� Opsonize bacteries
σ� Activate complement
σ� Cross placenta
165. The class of an immunoglobulin is determined by:
σ� Class I and II MHC
σ� The light chain
σ� The antigen
σ� The heavy chain
166. Light chains are :
σ� Specific for each class of antibody
σ� Complement fixation
σ� Reactive with antigen
σ� Have only a constant region
167. Each of the following statement is a characteristic of antibodies, EXCEPT:
σ� They have four glycoprotein chains
σ� They contain variable region
σ� They are phagocytes
σ� They have specific receptor for antigen
168. Cytokines are produced by cells of the immune system in response to various antigen, EXCEPT:
σ� Activate cell function
σ� Facilitate cell lysis
σ� Opsonization antigen
σ� Cause histamine release
169. The following answer is NOT true for interleukins?:
σ� Produced by T cells
σ� Regulation between cells
σ� They are not in stock
σ� Produced by antigen
170. Which of the following are true statements:
σ� IgM and IgG can fix complement
σ� IgA can fix complement
σ� IgE lyses allergen
σ� IgD provides immunization
171. An antigenic determinant is:
σ� A fragment of Antigen
σ� Recognized by a epitope
σ� Molecule of antigen
σ� Recognized by macrophage
172. The following statement is the basic monomeric immunoglobulin unit, EXCEPT:
σ� Composed of glycoproptein chains
σ� Same protein type for all antibody classes
σ� Able to associate with J- chain to form multimers
σ� The receptor is TCR
173. Class II MHC proteins are:
σ� Recognized by the CD8 protein
σ� Used to kill cytotoxic T-cells
σ� Participate in T helper function
σ� Not able to carry an epitope
174. The following statement are for Class I MHC proteins, EXCEPT:
σ� Able to carry an antigen fragment
σ� Recognized by the CD8 protein
σ� Killed target cells by Tc cells
σ� Participate in T helper function
175. Which properties do the T-cell receptor and the antibody share in common:
σ� Both recognize antigen fragments
σ� Both are able to fix complement
σ� Both have constant regions
σ� Both are polypeptide chains
176. The specific type of functional activity of a T-cell following antigen recognition is determined by:
σ� Antigen receptor
σ� MHC class II presenting the antigen fragment
σ� carbohydrate side chains
σ� CD4 or CD8 can bind antigens
177. The following statement are MOST closely related to each, EXCEPT:
σ� Antigen
σ� Allergen
σ� Epitope
σ� Antibody
178. The Immunoglobulins are secreted by:
σ� Plasma cells
σ� T-cells
σ� B-cells
σ� Macrophages
179. Antigen-antibody reactions can result in the following:
σ� Killed antigen
σ� Complement fixation
σ� Virus neutralization
σ� All answers
180. Variable regions of immunoglobulin are:
σ� Able to fix complement
σ� N-terminal of heavy chains
σ� C-terminal of heavy chains
σ� Specific recognition of antigen
181. The J-chain of immunoglobulin is :
σ� Made only by epithelial cells
σ� Present in IgM
σ� Present in IgG
σ� Made by T cells
182. The T-cell receptor is:
σ� Recognized antigen fragments
σ� Secreted by the T-cell
σ� Recognized antibody
σ� Bivalent
183. The following statement are for Target cell lysis and destruction, EXCEPT:
σ� Cytotoxic T-cells recognizing specific epitopes on the target cell surface
σ� Perforin released from antigen-specific cytotoxic T-cells
σ� Complement binding to IgG and IgM which have bound to epitopes on the target cell
σ� Complement binding to IgE which have bound to epitopes on the cell surface
184. The following statement is true for helper T-cells :
σ� Helper cells recognize antigen with MHC class I
σ� Helper cells recognize antigen with MHC class I and II
σ� Cytotoxic cells recognize antigen with MHC class
σ� Helper cells recognize antigen with MHC class II
185. The following statement are true for Cytokines, EXCEPT:
σ� Control and regulate the immune response
σ� Lymphokines are cytokines
σ� Secreted by specialized cells
σ� Are complement
186. The function of cytokines are :
σ� Bind to MHC class I
σ� Specifically recognize antigens
σ� Production of complement
σ� Regulation the immune cells
187. All of the following are true, EXCEPT :
σ� An epitope is a fragment of a macromolecule
σ� The variable regions contain the antigen recognition site
σ� An antigenic determinant is a paratope
The class of an immunoglobulin is determined by its heavy chain
188. The Natural Killer T Cells work in the immune system :
σ� Adaptive immunity
σ� Link between Adaptive and Innate immune
σ� Innate immunity
σ� Adaptive immunity and Innate immunity
189. The following bonds is responsible for linking of antibody to its chains:
σ� Van der Waals forces
σ� Hydrophobic forces
σ� Hydrogen bonds
σ� Disulfide bonds
190. The following organs do not affect by hepatitis virus, EXCEPT:
σ� Heart
σ� Liver
σ� Brain
σ� Kidneys
191. Which of the following hepatitis viruses is RNA virus?:
σ� Hepatitis A virus
σ� Hepatitis E virus
σ� Hepatitis B virus
σ� Hepatitis G virus
192. The following hepatitis can be prevented by vaccination :
σ� Hepatitis B and C
σ� Hepatitis C and E
σ� Hepatitis D and C
σ� Hepatitis A and B
193. Which of the following immune cells are effective to destroying intracellular pathogens:
σ� T helper cells
σ� B cells
σ� Antibodies
σ� T cytolytic cells
194. The following activities are belong to the B-cells :
σ� Act as antigen-processing cells
σ� Antibodies response to antigens
σ� Differentiate into plasma cells
σ� Receptor antigen monovalent
195. Which of the following DOES NOT play a role in antigen presentation:
σ� MHC class I molecules
σ� MHC class II molecules
σ� MHC class III molecules
σ� Complement
196. The variable regions in the light chains participate in:
σ� Fc receptor binding.
σ� Epitope binding.
σ� Affinity of the complement receptors.
σ� Interaction of the Fab with cytokines.
197. Which type of antibody is MOST effective in activating complement?:
σ� IgG1
σ� IgG2
σ� IgG3
σ� IgM
198. Which of the following antibody fragments consists of a dimer of the heavy-chain constant region but lacks the CH1 domains?:
σ� F(ab)’2
σ� F(ab)'
σ� Fab
σ� Fc
199. Which part of antibody lack of constant domain:
σ� VL
σ� CL
σ� CL and CH
σ� CH
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