Oral Pharmacology, Prof. Tuy Thel(61-120)
61. Intravenous administration of epinephrine results in? 1. Increased systolic pressure. 2. Increased heart rate. 3. palpitations. 4. Respiratory depression.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
62. Which of the following should NOT be prescribed for a patient receiving warfarin(Coumadin®)? 1. Acetylsalicylic acid. 2. Oxycodone. 3. Ketorolac. 4. Codeine.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
63. Chronic alcoholism will ? 1. Cause impairment of liver fun ction. 2. Increase tendency to hemorrhage. 3. Delay healing. 4. Decrease the effectiveness of local anesthetics.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All are correct
64. When used for conscious sedation, nitrous oxide may ? 1. Produce signs of inherent myocardial depression. 2. Produce an indirect sympathomimetic action. 3. Cause the patient to sweat. 4. Produce numbness of the extremities.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above.
65. A patient presents with a diffuse cellulitis and lymphadenopathy. A superinfection with a penicillinase-producing staphylococcus is suspected. Which of the following antibiotics is the drug of choice for treating this condition?
Tetracycline.
Cephalexin.
Penicillin G.
Erythromycin.
Chloramphenicol.
66. An excess of which hormone is associated with increased sensitivity to epinephrine?
Testosterone.
Parathyroid hormone.
Insulin.
Thyroxin.
Estrogen. .
67. Which hormone from the anterior pituitary gland regulates the release of corticosteroid hormones from the adrenal cortex?
TSH thyroid stimulating hormone.
ACTH adrenocorticotropic hormone
FSH Follicle-stimulating hormone ( gonadotropin )
LH luteinizing hormone
Progesterone
68. Which of the following steroids can provoque Cushing's syndrome?
Estradiol.
Testosterone.
Prednisolone.
Progesterone.
Diethylstilbestrol.
69. For antibiotic agent to be useful in the treatment of pathology microorganism, the following criteria should be met:?
The concentration of the antibiotic achieved and maintained at the site of infection.
The agent should be low toxicity for the body.
Not promote resistance or create imbalance of the normal flora of the body.
The microorganism must be susceptible to the agent.
All above are correct.
70. The bactericidal antibiotic:?
Macrolides
Tetracycline
Clindamycin
Penicillin , Cephalosporin
71. The bacteriostatic antibiotic:?
Macrolides
Tetracycline
Clindamycin
All are corrects
72. Erythromycin belong to which classification of drug:?
Clindamycin
Lincomycin
Cephalosporin
Macrolide
73. Which of the following should NOT be administered to a patient with chest pain consistent with a myocardial infarction?
Epinephrine.
Nitroglycerin.
Oxygen.
Morphine.
Acetylsalicylic acid.
74. Indication of Erythromycin:?
Alternative to PNC
Oral infection
Sinusitis
Respiratory tract infection
All are corrects
75. What is the mechanism of action of Erythromycin:?
Bacteriostatic antibiotic
Bacteriocidal antibiotic
Antifungus
Broad spectrum
76. Why is tetracycline is prescribed for Periodontal disease:?
Tetracycline releases collgenase and breakdown collagen in (gingival,periodontal and bone) -
Tetracycline inhibit spreading bacterial infection
Tetracycline inhibit secretion of acetyl choline
Gram stain positve
77. Which of the following will produce hemostasis when applied topically?
Oxidized cellulose.
Absorbable gelatin sponge.
Microfibrillar collagen.
Topical bovine thrombin.
All are corrects.
78. The usual adult dosage of codeine administered orally is ?
500-1000mg.
250-500mg.
30-60mg.
2-5mg.
None of the above.
79. Which of the following drugs is (are) used to suppress pain? 1. Benzodiazepines. 2. Barbiturates. 3. Narcotic analgesics.
(1) only.
(2) only.
(3) only.
(1) and (3)
(2) and (3)
80. In drug synergism?
a drug acts beneficially in conjunction with another drug.
a drug accumulates in the body at a faster rate than it is destroyed or removed.
a drug is concentrated in the kidneys.
a drug produces active metabolites.
the concentration of the drug increases with time.
81. Vasoconstrictors have all of the following actions EXCEPT ?
Constrict vessels and decrease blood flow to the site of injection.
Absorption of LA into bloodstream is slowed, producing lower levels in the blood.
Higher LA concentration remains around the nerve increasing the LA's duration of action
Minimize bleeding at the site of administration
Increase bleeding at the site of administration
82. A patient who has until recently been on prolonged corticosteroid therapy may have?
increased bleeding time.
hyposensitivity to pain.
decreased tolerance to physiological stress.
an increased metabolic rate.
high level of plasmatic cortisol.
83. Which statement(s) is/are true about diazepam? 1. It improves performance rating of fine motor skills. 2. It is more toxic when taken with ethyl alcohol. 3. It is available without prescription in Canada. 4. It produces a typical dependence syndrome.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
84. Insulin reaction is characterized by? 1. nausea. 2. tachycardia. 3. sweating. 4. Mental confusion
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
85. Which is the most appropriate prophylactic antibiotic for a patient with mitral valve prolapse with regurgitation undergoing a surgical dental procedure?
Intravenous ampicillin.
Clindamycin per os.
Intravenous vancomycin.
Erythromycin per os.
Amoxicillin per os.
86. Which of the following has/have analgesic, antipyretic and anti-inflammatory effects?
Acetominophen.
Acetylsalicylic acid.
Bradykinin.
Acetominophen and Acetylsalicylic acid.
None of the above.
87. Which of the following conditions can makean older patient short of breath on mild exertion? 1. Anemia. 2. Cardiac failure. 3. Obesity. 4. Osteoarthritis.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
88. Which of the following medications is CONTRAINDICATED in the management of a patient who is taking Coumadin?
Acetominophen.
Penicillin.
Acetylsalicylic acid.
Codeine.
Clindamycin.
89. A patient has valvular heart disease and is allergic to penicillin. The most appropriate antibiotic to be used prophylactically is ?
erythromycin.
metronidazole.
amoxicillin.
tetracycline.
clindamycin
90. Q91/ Which drug(s) control(s) pain and reduce(s) inflammation? 1. Acetylsalicylic acid. 2. Acetaminophen. 3. Ibuprofen. 4. Meperidine HCl.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
91. Epinephrine in a local anesthetic solution will? 1. Decrease absorption of the anesthetic. 2. Assist hemostasis at the site of injection. 3. Prolong the action of the anesthetic agent. 4. Assist in post-operative healing.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
92. Which of the following would you NOT prescribe for a patient receiving Warfarin (Coumadin®)? 1. Acetylsalicylic acid. 2. Metronidazole. 3. Erythromycin. 4. Codeine.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
93. The current recommended regimen of antibiotic prophylaxis for a patient with a prosthetic heart valve and an allergy to penicillin is?
amoxicillin 3g orally one hour before procedure; then 1.5g six hours after initial dose.
amoxicillin 2g orally one hour before procedure only.
clindamycin 300mg orally one hour before procedure; then 150mg six hours after initial dose.
clindamycin 600mg orally one hour before procedure only.
erythromycin stearate, 2g orally two hours before procedure only.
94. Corticosteroids may be used for the management of? 1. allergy. 2. arthritis. 3. asthma. 4. Addison's disease.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All are corrects
95. Lidocaine (Xylocaine) ? 1. Is a local anesthetic agent. 2. Has topical anesthetic properties. 3. Is an antiarrhythmic agent. 4. Has anticonvulsant properties.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
96. Most anaphylactic reactions to penicillin occur? 1. When the drug is administered parenterally. 2. Within minutes after drug administration. 3. In patients who have already experienced an allergic reaction to the drug. 4. In patients with a negative skin test to penicillin allergy.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All of the above
97. Side effects of therapeutic doses of codeine may produce? 1. constipation. 2. drowsiness. 3. nausea. 4. Respiratory depression.
(1) (2) (3)
(1) and (3)
(2) and (4 )
(4) only
All are corrects
98. Which of the following antibiotics may be cross-allergenic with penicillin?
Neomycin.
Cephalexin.
Clindamycin.
Erythromycin.
Tetracycline
99. Which of the following is directly involved in the conversion of prothrombin to thrombin?
Sodium.
Calcium.
Fluoride.
Potassium.
Bicarbonate
100. For the conversion of prothrombin to thrombin which of the following is required ?
Fibrinogen
Vitamin K.
Proconvertin
Thrombokinase
101. Thiopentone sodium (Pentothal) provides all of the following advantages EXCEPT ?
smooth pleasant induction.
good sleep production.
rapid recovery.
acceptability for both young and old.
adequate length of operating time.
102. Cardiovascular collapse caused by a high circulating dose of a local anesthetic is due to?
histamine release
myocardial depression
vagal stimulation
medullary stimulation
103. A lingual nerve block will NOT anesthetize the?
lingual gingivae
posterior one-third of the tongue
anterior two-thirds of the tongue
parasympathetic fibers to the submaxillary salivary gland.
floor of the mouth
104. For a patient with a history of glaucoma and porphyria, the pharmaco-sedation technique preferred is?
intravenous diazepam
nitrous oxide.
intravenous secobarbital
intravenous thiopental
oral diazepam
105. Hydrolysis of anesthetic salts is facilitated by ?
a tissue pH between 5.0 and 7.0
a tissue pH above 7.0
a tissue pH below 5.0
lipophilic properties of the nerve fibres.
106. After giving buccal infiltration anesthesia for the removal of a maxillary premolar, the patient complains of a sharp pain in the cheek which blanches. This is a result of?
stimulating sympathetic nerves around an artery
injecting the solution too rapidly
injecting too much solution
intravenous injection
107. Which of the following drugs is most addictive?
Hydromorphone HCl
Morphine sulfate
Meperidine
Codeine.
Oxycodone.
108. Bradycardia is a term that describes a heart rate of?
81-100 per minute
less than 60 per minute
61-80 per minute
over 100 per minute
109. Which of the following drugs is used in treating opioid-dependent individuals?
Alphaprodine.
Methadone
Codeine.
Meperidine.
Pentazocine.
110. A natural alkaloid obtained from opium is?
Meperidine.
Codeine
Hydromorphone
Methadone
111. Which properties increase the tendency of a drug to cross membranes?
Ionized and low lipid solubility
Non-ionized and high lipid solubility
Non-ionized and low lipid solubility
Ionized and water solubility
112. All of the following are possible effects of acetylsalicylic acid except?
suppression of inflammatory response
shortening of bleeding time
reduction of fever
bleeding from the gastrointestinal tract
113. Atropine acts as a/an?
antispasmodic
anticholinergic
sympatheticomimetic
antiemetic
114. The following drugs have a tendency to produce blood dyscrasia EXCEPT?
Phenylbutazone
Codeine
Indomethacin
Chloramphenicol.
115. During drug-receptor interaction, local anesthetics interfere with the transport of which of the following ions?
Chloride
Sodium
Calcium
Magnesium
Potassium
116. The principal difference between potassium, procaine and benzathine salts of penicillin G is their?
toxicity
duration of action
potency
diffusion into the cerebrospinal fluid
antibacterial spectrum.
117. Which antibiotic is chiefly bactericidal?
Tetracycline.
Penicillin
Erythromycin.
Clindamycin.
Chloramphenicol.
118. If an infection does not improve with penicillin therapy,?
penicillin allergy should be suspected
you should assume that a gram-negative organism is the causative agent
bacteria should be tested for penicillin-sensitivity
the dose of penicillin should be increased
119. A major secondary therapeutic use of the phenothiazines is as an?
anticonvulsant.
antiemetic
antidepressant.
antihypertensive.
120. Which of the following does NOT relieve pain?
Methadone.
Chloral hydrate
Codeine.
Hydromorphone
Meperidine.
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