10 Minute Quiz - Phar 300 - Oct 13 2020 - Dr Ruddock
Pharmaceutical Chemistry Quiz
Test your knowledge on medicinal chemistry with this engaging quiz designed for aspiring chemists and pharmaceutical professionals. Covering various topics from natural sources to drug metabolism, this quiz is an excellent way to challenge yourself and deepen your understanding.
Key features of the quiz:
- 11 insightful questions
- Focused on key concepts in medicinal chemistry
- Timed to enhance your decision-making skills
Medicinal chemistry is concerned with small organic molecules and biologics. Which group has biologics only?
Infliximab and atorvastatin
infliximab and erythropoietin
Erythropoietin and fluticasone
Fluticasone and atorvastatin
Which century saw the beginnings of modern organic chemistry and consequently of medicinal chemistry?
17th
18th
19th
20th
Salicin is isolated from which natural source?
Chinese Ephedra
Castor plant
Aspergillus terreus
Willow bark
Cytarabine (Ara-C) and vidarabine (Ara-A), the first FDA-approved marine-derived drugs, were developed from naturally occurring nucleosides originally isolated from the Caribbean sponge Tethya crypta. Which of the following is cytarabine used to treat?
Chronic myelogenous leukemia (CML)
Herpes simplex
Severe chronic pain
Metastatic breast cancer
What are the following characteristic of the ideal drug is false?
Show favourable binding characteristics to the receptor
Equilibrium will lie to the left
The drug will be expected to dissociate from the receptor
The drug will re-enter systemic circulation
The efficacy of enalaprilic acid (I) is enhanced by altering its chemical structure to enalpril (II) Which chemical methodology is employed in the conversion of I to II?
Hydrolysis
Dimerization
Esterification
Oxidation
The first pass effect occurs in which organ of the body?
The kidneys
The liver
The gastrointestinal tract
The skin
Rapid metabolism of lidocaine led to the development of tocainide which has a half life of how many hours?
2h
4h
7.5h
15h
Which sequence is correct? In enterohepatic circulation ,the drug re-enters the __A_____ from the _B__ _ through the ___C____
Intestinal tract, liver, bile duct
Bile duct, Intestinal tract, liver
Liver, bile duct, Intestinal tract
Intestinal tract, bile duct, Liver
Which of following contains ONLY Phase I reactions?
Glutathionation, acetylation, sulfonation
Oxidation, acetylation, hydrolysis
Hydrolysis, Reduction, sulfonation
Oxidation, Hydrolysis, reduction
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