Week 1- Blood
Understanding Blood: A Quiz for Knowledge Seekers
Test your understanding of the complex world of blood and hematology with our engaging quiz. Dive into topics ranging from erythropoiesis to iron metabolism, and deepen your knowledge about critical aspects of blood physiology.
- Explore the role of key proteins and hormones
- Learn about anemia types and their characteristics
- Challenge yourself with multiple-choice questions
What is the role of HIF1α in creation of new blood cells
HIF1α binds with oxygen in the lung, this stimulates the production of erythropoietin
HIF1α binds with oxygen in the lung, this inhibits the production of erythropoietin
HIF1α binds with oxygen in the kidney, this stimulates the production of erythropoietin
HIF1α binds with oxygen in the kidney, this inhibits the production of erythropoietin
In regards to the relationship between haemoglobin and oxygen, what does the term 'cooperative binding' mean?
The first bound oxygen molecule attaching to heme increases the affinity for subsequent molecules to bind also
Due to the nature of the porphryn ring in haemaglobin, oxygen is the preferred binding molecule. The iron of the porphryn ring and the oxygen molecules demonstrate a 'cooperative' relationship
Cooperative binding is the term used to describe the passive exchange within haemaglobin between oxygen and carbon dioxide
In haemaglobin, cooperative binding refers to the ease in which oxygen can be both bound and released
In patients suffering typical Iron Deficiency Anaemia, what would an expected mean corpuscular volume be
Below 80fL
80 to 100fL
Above 100fL
Iron Deficiency Anaemia would not affect mean corpuscular volume
What is the name of the protein that allows safe storage of iron within cells?
Ferrous Reductase
Transferrin
Hepcidin
Ferritin
How does TNFα contribute to anemia in Anaemia of Chronic Disease?
Blocks the uptake of erythropoietin by bone marrow
Stimulates the proliferation of meglaoblasts
Inhibits the production of erythropoetin from the kidney
Prevents iron absorbtion in the duodenum
What is the role of haptocorrin in B12 absorbtion
Stimulares the production of Intrinsic Factor in the stomach
Prevents digestion in the stomach
Prevents digestion during transfer through the small bowel
Cleaves B12 from Intrinsic Factor prior to absorbtion in the small bowel
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