HistaFer

Iron is an essential macronutrient that is tied to many bodily functions. Ideally, most people will meet their iron needs through diet.
True
False
Heme in hemoglobin contains how many iron molecule?
1
2
3
4
Hemoglobin comprises of how many sub units ?
1
2
3
4
There are 4 Heme groups each in every individual sub-unit of Hemoglobin.
True
False
Hemoglobin is present in all parts of the body but absent in brain due to the presence of Blood Brain Barrier.
True
False
Histidine is one of the molecule that can cross the Blood Brain Barrier.
True
False
Histidine directly bind with hemoglobin at the alpha 1 and alpha 2 chain to provide cerebral oxygenation.
True
False
HistaFer is the only product with Iron Histidine without any other combination.
True
False
Which of the follow is/are the function(s) of Iron in Brain ?
Formation of Synaptic Cleft
Regulation of Long Term Pontentiation
Transportation of oxygen to the Brain
All the Above
Which of the following is/are the function(s) of Histidine in Brain ?
It is the biosynthetic precursor of the neurotransmitter histamine (HA).
What is the main function of histidine? It's used in growth, repair of damaged tissues
Histidine is required as a precursor of carnosine in human muscle and parts of the brain
All the above
Transferrin is a glycoprotein which a __________
Helps in transportation of Histidine
Helps in the transportation of Oxygen
Helps in the transportation of Iron
Helps in the transportation of Hemoglobin
Iron affects synthesis and signaling of which neurotransmitter(s)
Dopamine
Adrenaline
Noradrenaline
All the above
The brain has a high energy demand, accounting for ________ of basal oxygen consumption
20%
45%
15%
30%
Reduced mitochondrial efficiency due to iron deficiency possibly results in elevation of ____________
Mitochondrial Dysfunction
Oxidative Stress
Hyperpolarization
Metabolic Imbalance
________ is a fatty “white matter” that insulates axons and preserves their signaling
Axon
Microglia
Astrocytes
Myelin
Iron deficiency, characterized by __________, has been associated with several developmental neurological disorders such as poorer fine and gross motor skills, visual-motor integration etc.
Glycemia
Hypoglycemia
Anemia
Hypercalcemia
Haemoglobin forms an unstable & reversible bond with __________
Nitrogen
Oxygen
Iron
Histidine
___________ form of Iron binds to Oxygen atoms with strong bond
Ferritin
Ferric
Ferrous
Ferrites
Desaturated Haemoglobin is called as Oxy Haemoglobin
True
False
Myoglobin is composed of Single Peptide Chain that oxygen in Muscles
True
False
In co-operative oxygen binding when O2 binds to Heme group then ______ more oxygen binds with remaining heme group of the a single hemoglobin
1
2
3
4
When the Fe atom moves into the porphyrin plane after oxygenation, the ____________ histidine which is attached to the Fe is drawn closer to the Heme group.
Proximal
Distal
Both
None
Histidine is an essential ammino acid as it synthesized by the body itself.
True
False
Proximal and Distal Histidine are only 2 forms of Histidine and not separate 2 different types of Histidine.
True
False
Mother’s breast milk doesn’t contains Histidine.
True
False
Histidine is a Chelator of Fe & Enhances its absorption in the Haemoglobin
True
False
Histafer can also be recommended for Iron deficiency anemia
True
False
Elemental iron in HistaFer Syrup is ___________
5mg/ml
6g/ml
5g/ml
6mg/ml
PTS of HistaFer Syrup is _________
384.41
348.81
348.41
384.81
What is the the function of Blood ?
Transportation of Oxygen
Transportation of Nutrition
Connection all the major organs of the body
All the above.
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